299159-27-6

Usage

Uses

Used in Pharmaceutical Industry:
4-(4-Iodobenzyl)morpholine is used as an intermediate in the synthesis of various pharmaceuticals for its ability to serve as a building block in medicinal chemistry. It contributes to the development of potential drug candidates due to its unique structural features.
Used in Agrochemical Industry:
In the agrochemical sector, 4-(4-Iodobenzyl)morpholine is utilized as an intermediate in the production of agrochemicals, playing a role in the synthesis of compounds that can enhance crop protection and yield.
Used in Organic Compounds Synthesis:
4-(4-Iodobenzyl)morpholine is employed as a key intermediate in the synthesis of a range of organic compounds, leveraging its reactive sites for the formation of new chemical entities with desired properties.
Used in Materials Science:
4-(4-Iodobenzyl)morpholine may be used in materials science applications, capitalizing on its unique chemical properties to develop new materials with specific characteristics for various industrial uses.

InChI:InChI=1/C11H14INO/c12-11-3-1-10(2-4-11)9-13-5-7-14-8-6-13/h1-4H,5-9H2

Upstream product

• 110-91-8 morpholine 
• 16004-15-2 1-bromomethyl-4-iodobenzene 
• 15164-44-0 p-(iodophenyl)carboxaldehyde 

Downstream Products

• 1093189-87-7 C₁₄H₁₇NO₂ 
• 1093190-80-7 4-(4-morpholin-4-ylmethylphenylsulfanyl)benzoic acid methyl ester 
• 1207176-34-8 3-{[4-(morpholin-4-ylmethyl)phenyl]amino}-1-phenyl-1H-pyrazole-4-carbonitrile 
• 1295647-21-0 (6R,12aR)-6-benzo[1,3]dioxol-5-yl-2-(4-morpholin-4-ylmethylphenyl)-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione 
• 1548043-14-6 (S)-5-(4-{[4-(morpholinomethyl)phenyl]ethynyl}phenyl)-1,4-dioxan-2-one 
• 1548043-68-0 (R)-5-(4-{[4-(morpholinomethyl)phenyl]ethynyl}phenyl)-1,4-dioxan-2-one 
• 1093190-84-1 N-((1S,2R)-2-hydroxy-1-hydroxycarbamoylpropyl)-4-(4-morpholin-4-ylmethylphenylsulfanyl)benzamide trifluoroacetate 
• 1093189-96-8 C₂HF₃O₂*C₂₂H₂₁NO₃ 
• 1093189-93-5 C₂HF₃O₂*C₂₂H₂₁NO₃ 
• 1093190-00-1 C₃₀H₃₆N₄O₆ 
• 1093189-99-1 C₃₁H₃₇N₃O₆ 
• 1093190-81-8 4-(4-morpholin-4-ylmethylphenylsulfanyl)benzoic acid hydrochloride 
• 1093190-82-9 (2S,3R)-3-hydroxy-2-(4-(4-morpholin-4-ylmethylbenzylsulfanyl)benzoylamino)butyric acid methyl ester 
• 1093189-90-2 C₂₂H₂₁NO₃ 

Relevant academic research and scientific papers

C(sp3)-H Monoarylation of Methanol Enabled by a Bidentate Auxiliary

With the assistance of a practical directing group (COAQ), the first catalytic protocol for the palladium-catalyzed C(sp3)-H monoarylation of methanol has been developed, offering an invaluable synthesis means to establish extensive derivatives of crucial arylmethanol functional fragments. Furthermore, the gram-scale reaction, broad substrate scope, excellent functional group compatibility, and even the practical synthesis of medicines further demonstrate the usefulness of this strategy.

ETHYNYLBENZENE DERIVATIVES

Disclosed are compounds of formulae (I), (II), and (II)I: and pharmaceutically acceptable salts thereof, wherein the variables, R, R1, R2, R3, R101, L, D, Q, Y, X, and Z are defined herein. These compounds are useful for treating Gram-negative bacteria infections.

ANTIBACTERIAL AGENTS

Antibacterial compounds of formula (I) are provided, as well as stereoisomers, pharmaceutically acceptable salts, esters, and prodrugs thereof; pharmaceutical compositions comprising such compounds; methods of treating bacterial infections by the administration of such compounds; and processes for the preparation of such compounds.

SPIRO-OXAZOLIDINONE COMPOUNDS AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR POTENTIATORS

Compounds in accord with Formula (I): wherein R1, L, A, B, D, E, m, n, x and y are as defined in the description, processes for the preparation of such compounds and to new intermediates employed in the preparation thereof, pharmaceutical compositions containing such compounds, and the use of such compounds in therapy and for the treatment of diseases mentioned in the specification.

PHOSPHODIESTERASE 4 INHIBITORS, INCLUDING N-SUBSTITUTED ANILINE AND DIPHENYLAMINE ANALOGS

PDE4 inhibition is achieved by novel compounds, e.g., N-substituted aniline and diphenylamine analogs. The compounds of the present invention are of Formula (I): wherein R1, R2 R 3 and R4 are as defined herein.