299202-10-1Relevant academic research and scientific papers
Recyclable, magnetic ionic liquid bmim[FeCl4]-catalyzed, multicomponent, solvent-free, green synthesis of quinazolines
Panja, Sumit Kumar,Saha, Satyen
, p. 14495 - 14500 (2013)
An atom-efficient, eco-friendly, solvent-free, high yielding, multicomponent green strategy to synthesize highly functionalized quinazoline derivatives by the one-pot reaction of 2-aminobenzophenone, aromatic aldehyde and ammonium acetate is presented. Ma
A convenient access to 2,4-disubstituted quinazolines via one-pot three-component reaction under mild conditions?
Bose, D. Subhas,Ramesh, Nukala
supporting information, p. 1495 - 1503 (2020/04/27)
A new and practical method has been developed for the synthesis of 2,4-disubstituted quinolines via one-pot three-component reaction of o-amino arylketones, aldehydes and ammonium acetate in high yields by using DDQ in CH3CN under mild conditio
TMSOTf-catalyzed synthesis of substituted quinazolines using hexamethyldisilazane as a nitrogen source under neat and microwave irradiation conditions
Chan, Chieh-Kai,Lai, Chien-Yu,Wang, Cheng-Chung
, p. 7201 - 7212 (2020/10/02)
In this article, we report an efficient and mild synthetic route for the construction of substituted quinazolines from functionalized 2-aminobenzophenones with various benzaldehydes usingcat. TMSOTf and hexamethyldisilazane (HMDS) under neat, metal-free and microwave irradiation conditions in which gaseous ammonia was formedin situ. This synthetic protocol provided the desired quinazolines with a broad substrate scope in good to excellent yields. Some structures were confirmed by X-ray single-crystal diffraction analysis.
I2-Catalyzed three-component protocol for the synthesis of quinazolines
Panja, Sumit Kumar,Dwivedi, Nidhi,Saha, Satyen
supporting information, p. 6167 - 6172 (2012/11/14)
An efficient and one-pot three-component strategy for synthesizing highly functionalized quinazoline derivatives is presented. A mixture of 2-aminobenzophenone, aromatic aldehyde and ammonium acetate in the presence of I2-catalyst provides desired product
Catalyst-free synthesis of quinazoline derivatives using low melting sugar-urea-salt mixture as a solvent
Zhang, Zhan-Hui,Zhang, Xiao-Nan,Mo, Li-Ping,Li, Yong-Xiao,Ma, Fei-Ping
experimental part, p. 1502 - 1506 (2012/06/04)
Low melting mixture of maltose-dimethylurea (DMU)-NH4Cl was found to be an inexpensive, non-toxic, easily biodegradable and effective reaction medium in the catalyst-free synthesis of quinazoline derivatives. This simple and efficient method fu
