Cas 299217-07-5,4-acetoxy-5-(4-benzyl-phenyl)-5,5-difluoro-pentanoic acid

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Check Digit Verification of cas no

The CAS Registry Mumber 299217-07-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,9,9,2,1 and 7 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 299217-07:
(8*2)+(7*9)+(6*9)+(5*2)+(4*1)+(3*7)+(2*0)+(1*7)=175
175 % 10 = 5
So 299217-07-5 is a valid CAS Registry Number.

299217-07-5Upstream product

299217-07-5Downstream Products

299217-08-6 5-(4-Benzyl-phenyl)-5,5-difluoro-4-hydroxy-pentanoic acid ((S)-2,2-dimethyl-1-methylcarbamoyl-propyl)-amide

299217-07-5Relevant academic research and scientific papers

Difluoroketones as inhibitors of matrix metalloprotease-13

Reiter, Lawrence A.,Martinelli, Gary J.,Reeves, Lisa A.,Mitchell, Peter G.

, p. 1581 - 1584 (2000)

Substrate-like difluoroketones have been prepared as potential inhibitors of MMP-13. Weak inhibition was seen with the key target 2. This and the more potent activity of intermediate 7b illustrates that hydrated ketones can be used to inhibit MMP-13 and perhaps other members of this class of enzymes. (C) 2000 Elsevier Science Ltd. All rights reserved.

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