2993-22-8 Usage
Description
3-AMINOPHENYLSULFUR PENTAFLUORIDE, also known as pentafluoroaniline, is a perfluoroaromatic compound with a unique chemical structure. It possesses a sulfur atom bonded to a phenyl ring with three fluorine atoms and an amino group attached to it. 3-AMINOPHENYLSULFUR PENTAFLUORIDE is known for its reactivity and stability, making it a versatile molecule for various applications.
Uses
Used in Chemical Synthesis:
3-AMINOPHENYLSULFUR PENTAFLUORIDE is used as a reagent for the reduction of pentafluoroaniline (PFA), leading to rapid fluoride elimination and the formation of the aminotetrafluorophenyl radical. This radical can then participate in homolytic reactions with other aromatic compounds, allowing for the synthesis of novel and complex molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3-AMINOPHENYLSULFUR PENTAFLUORIDE is used as an intermediate for the synthesis of various drugs and drug candidates. Its unique chemical properties enable the development of new compounds with potential therapeutic applications.
Used in Material Science:
3-AMINOPHENYLSULFUR PENTAFLUORIDE is used as a building block for the development of new materials with specific properties, such as improved stability, reactivity, or selectivity. These materials can be applied in various fields, including electronics, coatings, and adhesives.
Used in Research and Development:
3-AMINOPHENYLSULFUR PENTAFLUORIDE is used as a research tool for studying the properties and reactivity of perfluoroaromatic compounds. Its unique structure allows scientists to gain insights into the behavior of these compounds and develop new strategies for their synthesis and application.
Check Digit Verification of cas no
The CAS Registry Mumber 2993-22-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,9,9 and 3 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 2993-22:
(6*2)+(5*9)+(4*9)+(3*3)+(2*2)+(1*2)=108
108 % 10 = 8
So 2993-22-8 is a valid CAS Registry Number.
InChI:InChI=1/C6H6F5NS/c7-13(8,9,10,11)6-3-1-2-5(12)4-6/h1-4H,12H2
2993-22-8Relevant articles and documents
Synthesis and characterisation of 3- and 4-(pentafluorosulfanyl)benzoic acid derivatives. X-ray structure of 3-SF5-C6H4-COOH
Zarantonello,Guerrato,Ugel,Bertani,Benetollo,Milani,Venzo,Zaggia
, p. 1449 - 1453 (2007)
The high yield synthesis of 3- and 4-(pentafluorosulfanyl)benzoic acid derivatives is described starting from the NO2-derivatives, which are reduced to the corresponding anilines. Then the NH2- group is converted to bromide and subsequently to the HC{double bond, long}O moiety. The benzaldeydes are then oxidised to the corresponding benzoic acids. The X-ray structure of 3-SF5-C6H4-COOH is also reported.
METHOD FOR PRODUCING NITROGEN-CONTAINING PENTAFLUOROSULFANYLBENZENE COMPOUND
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Paragraph 0098; 0099; 0100; 0101, (2018/01/11)
A method for producing a nitrogen-containing pentafluorosulfanylbenzene compound of formula (2a) or (2b): (wherein R1 a hydrogen atom or a hydrocarbon group; Z is an aryl group linked to a carbonyl group; Y is a group of formula (Y1), (Y2), (Y3), or (Y4); R2 is a hydrogen atom or a hydrocarbon group) the method comprising reacting a halogeno-pentafluorosulfanylbenzene compound of formula (1) with a nitrogenous nucleophile: (wherein X is a halogen atom; n is an integer of 1 to 5; R1 is as defined above).
Ir-catalyzed preparation of SF5-substituted potassium aryl trifluoroborates via C-H borylation and their application in the Suzuki-Miyaura reaction
Joliton, Adrien,Carreira, Erick M.
supporting information, p. 5147 - 5149 (2013/11/06)
The preparation of new pentafluorosulfanyl-substituted potassium aryltrifluoroborates via Ir-catalyzed C-H borylation is reported. The utility of these novel building blocks was demonstrated in the Suzuki-Miyaura cross-coupling reaction, giving access to
