299405-04-2

Basic information

• Product Name: ethyl 2-{[(2-chlorophenyl)carbonyl]amino}-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate
• Synonyms: ethyl 2-{[(2-chlorophenyl)carbonyl]amino}-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate
• CAS NO: 299405-04-2
• Molecular Formula: C18H18ClNO3S
• Molecular Weight: 363.85842
• Mol File: 299405-04-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 472.7±45.0 °C(Predicted)
• Appearance: /
• Density: 1.342±0.06 g/cm3(Predicted)
• PKA: 12.04±0.20(Predicted)
• CAS DataBase Reference: ethyl 2-{[(2-chlorophenyl)carbonyl]amino}-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-{[(2-chlorophenyl)carbonyl]amino}-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate(299405-04-2)
• EPA Substance Registry System: ethyl 2-{[(2-chlorophenyl)carbonyl]amino}-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate(299405-04-2)

Safety Data

• Hazardous Substances Data: 299405-04-2(Hazardous Substances Data)

Upstream product

• 141-97-9 ethyl acetoacetate 
• 4506-71-2 ethyl 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate 
• 609-65-4 o-chlorobenzoyl chloride 
• 118-91-2 ortho-chlorobenzoic acid 

Relevant articles and documents

Preparation method and application of tetrahydrobenzothiophene compound and pharmaceutical composition

The invention belongs to the field of medicines, and particularly relates to a tetrahydrobenzothiophene compound as well as a pharmaceutical composition and a preparation method and application thereof. The tetrahydrobenzothiophene compound is a compound I as shown I. In-flight R1 And R2 The C1 -4 is a saturated/unsaturated hydrocarbon group. - OCH3 , OCH2 CH3 Phenyl, substituted phenyl, NO2 One - COR of - OH - F, Cl - Br. I - H R1 AND R2 Or different. R3 It is-F. - Cl, Br, I, OH, Amino, C1 -4 saturated/unsaturated hydrocarbon group, OCH3 , OCH2 CH3 , H, Wherein one of them is, n ≥ 5, n Being an integer. The compound effectively inhibits salmonella by inhibiting the synthesis of ATP-dependent transporter in the lipopolysaccharide synthesis pathway. Aeruginosa, escherichia coli and staphylococcus aureus.