29941-86-4

Upstream product

• 109-86-4 2-methoxy-ethanol 
• 765-87-7 cyclohexane-1,2-dione 
• 111-30-8 Glutaraldehyde 
• 113371-37-2 2-cyano-6-methoxytetrahydropyran 
• 113371-44-1 6-Methoxy-2-(2-methoxy-ethoxymethyl)-tetrahydro-pyran-2-carbonitrile 

Downstream Products

• 144572-83-8 (3S,4R)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-4-[(1S,3S)-3-(2-methoxy-ethoxy)-2-oxo-cyclohexyl]-azetidin-2-one 
• 181657-29-4 (3S,4R)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-4-[(1R,3S)-3-(2-methoxy-ethoxy)-2-oxo-cyclohexyl]-azetidin-2-one 
• 181657-32-9 {(2R,3S)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-2-[(1S,3S)-3-(2-methoxy-ethoxy)-2-oxo-cyclohexyl]-4-oxo-azetidin-1-yl}-oxo-acetic acid allyl ester 
• 181421-92-1 {(2R,3S)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-2-[(1R,3S)-3-(2-methoxy-ethoxy)-2-oxo-cyclohexyl]-4-oxo-azetidin-1-yl}-oxo-acetic acid allyl ester 

Relevant academic research and scientific papers

Synthesis and biological evaluation of 4-alkoxy substituted trinems. Part 1

Synthesis of new 4-alkoxy substituted trinems 4, 5, 6, 7 and 8 together with their antibacterial profiles compared to imipenem and GV104326 (2) are described. The good antibacterial profile observed for derivatives 4-7 encouraged further exploration of these derivatives.

2-CYANO-6-METHOXYTETRAHYDROPYRAN, A USEFUL PROTECTED CYANOHYDRIN FOR 2-SUBSTITUTED CYCLOHEXENONE SYNTHESIS

The title compound 1, easily prepared from commercially available glutaraldehyde, is a protected cyanohydrin useful as synthon for the preparation of 2-substituted cyclohexenones.