299417-31-5

Basic information

• Product Name: 2-Thiazolamine, 5-(1,1-dimethylethyl)-
• Synonyms: 2-Thiazolamine, 5-(1,1-dimethylethyl)-;5-tert-butyl-1,3-thiazol-2-amine;MFCD02170355;5-(tert-butyl)thiazol-2-amine
• CAS NO: 299417-31-5
• Molecular Formula: C₇H₁₂N₂S
• Molecular Weight: 156.25
• Mol File: 299417-31-5.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 253.2±9.0 °C(Predicted)
• Appearance: /
• Density: 1.107±0.06 g/cm3(Predicted)
• PKA: 5.48±0.10(Predicted)
• CAS DataBase Reference: 2-Thiazolamine, 5-(1,1-dimethylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Thiazolamine, 5-(1,1-dimethylethyl)-(299417-31-5)
• EPA Substance Registry System: 2-Thiazolamine, 5-(1,1-dimethylethyl)-(299417-31-5)

Safety Data

• Hazardous Substances Data: 299417-31-5(Hazardous Substances Data)

Usage

General Description

2-Thiazolamine, 5-(1,1-dimethylethyl)- is a chemical compound with a molecular formula of C8H12N2S. It is a thiazole amine derivative with a tert-butyl group attached to the fifth carbon atom. 2-Thiazolamine, 5-(1,1-dimethylethyl)- is commonly used as a building block in organic synthesis and drug discovery. It has potential applications in the pharmaceutical industry, particularly in the development of new medications. Additionally, it may also have uses in research and development for various scientific and industrial purposes.

Upstream product

• 420-04-2 CYANAMID 
• 2987-16-8 3,3-dimethylbutyrylaldehyde 
• 123-75-1 pyrrolidine 
• 96-50-4 2-thiazolylamine 
• 75-65-0 tert-butyl alcohol 

Downstream Products

• 1065641-00-0 3-(but-3-ynyl)-5-tert-butylthiazol-2(3H)-imine 
• 1187465-77-5 (R,Z)-tert-butyl 1-(5-tert-butyl-2-(5-chloro-2-methoxybenzoylimino)thiazol-3(2H)-yl)propan-2-ylcarbamate 
• 1187464-88-5 N-[(2Z)-5-tert-butyl-3-{[(2R)-5-oxopyrrolidin-2-yl]methyl}-1,3,4-thiadiazol-2(3H)-ylidene]-5-chloro-2-methoxybenzamide 
• 1232169-34-4 N-[(2Z)-5-tert-butyl-1,3-thiazol-2(3H)-ylidene]-2-fluoro-5-(trifluoromethyl)benzamide 
• 959749-10-1 5-tert-butyl-3-[(2R)-tetrahydrofuran-2-ylmethyl]-1,3-thiazol-2(3H)-imine p-toluenesulfonic acid 
• 943774-47-8 N-(5-tert-butyl-thiazol-2-yl)-4-chloro-3-nitro-benzamide 
• 959749-16-7 N-(5-tert-butylthiazol-2-yl)-5-chloro-2-methoxybenzamide 

Relevant articles and documents

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INHIBITING UBIQUITIN SPECIFIC PEPTIDASE 30

The present disclosure relates to chemical entities useful as inhibitors of Ubiquitin Specific Peptidase 30 (USP30), pharmaceutical compositions comprising the chemical entities, and methods of using the chemical entities. The chemical entities as disclosed herein can be useful in the treatment of a disease, disorder, or condition involving mitochondrial dysfunction, including neurodegenerative diseases, motor neuron diseases, metabolic disorders, and cancers, among other ailments.

NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS AND USES THEREOF

The present invention relates to compounds of formula (I), or pharmaceutical salts, prodrugs, salts of prodrugs, or combinations thereof, formula (I). wherein R1, R2, R3, R4, and L1 are defined in the specfication, compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions. The present invention also relates to compounds of formula (II), or pharmaceutical salts, prodrugs, salts of prodrugs, or combinations thereof, formula (II). wherein R1a, R2a, Rx, and n are as defined in the specification, compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions.