299434-73-4

Basic information

• Product Name: 4-benzyl-3-cyclopropylethynyl-3-trifluoromethyl-1-(2-trimethylsilanyl-ethoxymethyl)-3,4-dihydro-1H-quinoxalin-2-one
• CAS NO: 299434-73-4
• Molecular Weight: 500.636
• Mol File: 299434-73-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-benzyl-3-cyclopropylethynyl-3-trifluoromethyl-1-(2-trimethylsilanyl-ethoxymethyl)-3,4-dihydro-1H-quinoxalin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-benzyl-3-cyclopropylethynyl-3-trifluoromethyl-1-(2-trimethylsilanyl-ethoxymethyl)-3,4-dihydro-1H-quinoxalin-2-one(299434-73-4)
• EPA Substance Registry System: 4-benzyl-3-cyclopropylethynyl-3-trifluoromethyl-1-(2-trimethylsilanyl-ethoxymethyl)-3,4-dihydro-1H-quinoxalin-2-one(299434-73-4)

Safety Data

• Hazardous Substances Data: 299434-73-4(Hazardous Substances Data)

Upstream product

• 253690-77-6 3-(trifluoromethyl)-1-((2-(trimethylsilyl)ethoxy)methyl)quinoxalin-2(1H)-one 
• 58457-64-0 3-(trifluoromethyl)quinoxalin-2(1H)-one 
• 95-54-5 1,2-diamino-benzene 
• 253690-82-3 3-cyclopropylethynyl-3-trifluoromethyl-1-(2-trimethylsilanyl-ethoxymethyl)-3,4-dihydro-1H-quinoxalin-2-one 

Relevant articles and documents

Synthesis and evaluation of quinoxalinones as HIV-1 reverse transcriptase inhibitors

A series of 3,3-disubstituted quinoxalinones was prepared and evaluated as HIV-1 reverse transcriptase inhibitors. The N-allyl (6b and 6f), N-cyclopropylmethyl (6a, 6g, 6h and 6k) and N-carboalkoxy (6m-6y) substituted compounds displayed activity comparable or better than Efavirenz and GW420867X. (C) 2000 Dupont Pharmaceuticals Company. Published by Elsevier Science Ltd. All rights reserved.