29945-90-2

Usage

Type of compound

Alkyne derivative

Chemical structure

Pent-4-ynamide group with two methyl substituents on the second carbon atom

Usage

Building block in organic synthesis and pharmaceutical research

Reactivity

Can undergo various reactions to produce different compounds with potential use in medicinal chemistry, materials science, and other fields

Value

Valuable tool in the development of new chemical compounds and materials.

Upstream product

• 86101-48-6 2,2-dimethylpent-4-ynoic acid 
• 29945-89-9 2,2-dimethyl-4-pentynenitrile 

Relevant academic research and scientific papers

Toward the synthesis of biologically important chlorins, isobacteriochlorins, and corrins. Cyclic enamides from acetylenic amides

Cyclic enamides 1 of a type useful in the synthesis of naturally occurring chlorins, isobacteriochlorins, and corrins have been prepared by a process involving 5-exo-dig cyclization of the appropriate acetylenic amides 11. The desired cyclization is catalyzed by either n-Bu4NF or LiAl-(NHBn)4.

Synthesis of Cyclic Enamides by Intramolecular Cyclization of Acetylenic Amides.

Cyclic enamides 12 of a type useful in the synthesis of naturally occuring chlorins, isobacteriochlorins, and corrins have been prepared by a process involving Nicholas-Schreiber condensation to afford acetylenic amides 13, followed by either n-Bu4NF- or