299451-66-4Relevant academic research and scientific papers
Mo@GAA-Fe3O4MNPs: a highly efficient and environmentally friendly heterogeneous magnetic nanocatalyst for the synthesis of polyhydroquinoline derivatives
Aghaei-Hashjin, Mehraneh,Yahyazadeh, Asieh,Abbaspour-Gilandeh, Esmayeel
, p. 10497 - 10511 (2021)
Polyhydroquinolines were efficiently obtained from a sequential four-component reaction between dimedone or 1,3-cyclohexandione, ethyl acetoacetate, or methyl acetoacetate as a β-ketoester, aldehydes, and ammonium acetate, under the catalysis of Mo@GAA-Fe3O4MNPs as a green, effective, recyclable, and environmentally friendly nanocatalyst. Due to its magnetic nature the prepared catalyst can be easily separated from the reaction mixture by an external magnet and reused several times without significant changes in catalytic activity and reaction efficiency. The catalyst was characterized using energy dispersive X-ray spectroscopy (EDX), X-ray diffraction (XRD), thermogravimetric analysis (TGA), Fourier transform infrared spectroscopy (FTIR), vibrating sample magnetometry (VSM), scanning electron microscopy (SEM), and transmission electron microscopy (TEM).
Synthesis and antioxidant evaluation of novel 4-aryl-hexahydroquinolines from lignin
Yang, Xiao-Hui,Zhang, Ping-Hu,Zhou, Yong-Hong,Liu, Cheng-Guo,Lin, Xiao-Yu,Cui, Jing-Fang
experimental part, p. 327 - 337 (2011/12/15)
A series of 4-aryl-hexahydroquinolines were prepared by Hantzsch reaction using aromatic aldehydes obtained from lignin, 1,3-cyclohexanediones, β-ketoesters and ammonium carbonate. The antioxidant properties of compounds 5a-c and 5g-i were evaluated by two methods: scavenging effect on 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical and scavenging effect on 2,2′-azino-bis(3-ethylenzothiazoline-sulfonic acid) diammonium salt (ABTS+) radical. The results show that the compounds containing a methoxy moiety exhibit good activities. The study suggests that some synthesized compounds may serve as promising leads for the treatment against tumors or other free radical-related diseases.
A facile four component one-pot synthesis of polyhydroquinoline derivatives catalyzed by ionic liquid via modified Hantzsch reaction
Nirmal, Jay P.,Dadhaniya, Pratish V.,Patel, Manish P.,Patel, Ranjan G.
experimental part, p. 587 - 592 (2011/01/04)
An efficient and newer Hantzsch reaction for the synthesis of polyhydroquinoline derivatives have been reported via fourcomponent condensation of aldehydes, cyclic 1,3-diketones, β-keto esters, NH4OAc and catalytic amount of ionic liquid 1-Viny
