29946-62-1Relevant academic research and scientific papers
Unexpected PF 6 Anion Metathesis during the Bischler-Napieralski Reaction: Synthesis of 3,4-Dihydroisoquinoline Hexafluorophosphates and Their Tetrahydroisoquinoline Related Alkaloids
Puerto Galvis, Carlos E.,Macías, Mario A.,Kouznetsov, Vladimir V.
, p. 1949 - 1960 (2019/04/26)
A series of N -phenethylcinnamamides were subjected to the Bischler-Napieralski reaction to furnish diverse 1-styryl-3,4-dihydroisoquinolines. We noticed that the desired products were unstable when the reaction was performed under conventional solvent co
Dopaminergic isoquinolines with hexahydrocyclopenta[ ij ]-isoquinolines as D2-like selective ligands
Párraga, Javier,Andujar, Sebastián A.,Rojas, Sebastián,Gutierrez, Lucas J.,El Aouad, Noureddine,Sanz, M. Jesús,Enriz, Ricardo D.,Cabedo, Nuria,Cortes, Diego
, p. 27 - 42 (2016/07/06)
Dopamine receptors (DR) ligands are potential drug candidates for treating neurological disorders including schizophrenia or Parkinson's disease. Three series of isoquinolines: (E)-1-styryl-1,2,3,4-tetrahydroisoquinolines (series 1), 7-phenyl-1,2,3,7,8,8a
Synthesis of hexahydrocyclopenta[ ij ]isoquinolines as a new class of dopaminergic agents
Prraga, Javier,Galn, Abraham,Sanz, Maria Jess,Cabedo, Nuria,Cortes, Diego
, p. 101 - 106 (2015/01/08)
In this study, we have described the synthesis of the tricyclic 1,2,3,7,8,8a-hexahydrocyclopenta [ij]isoquinoline (HCPIQ). Herein, six differently substituted 5,6-dioxygenated-7-phenyl-HCPIQs have been synthesized using a new methodology via (E)-1-styryl-
Synthesis of hexahydrocyclopenta[ ij[isoquinolines as a new class of dopaminergic agents
Párraga, Javier,Galán, Abraham,Sanz, Maria Jesús,Cabedo, Nuria,Cortes, Diego
, p. 101 - 106 (2015/05/26)
In this study, we have described the synthesis of the tricyclic 1,2,3,7,8,8a-hexahydrocyclopenta [ij]isoquinoline (HCPIQ). Herein, six differently substituted 5,6-dioxygenated-7-phenyl-HCPIQs have been synthesized using a new methodology via (E)-1-styryl-
