29958-08-5

Basic information

• Product Name: 2-(Methylthio)-5-aminopyridine
• Synonyms: 2-(Methylthio)-5-aminopyridine;6-(methylthio)-3-Pyridinamine;6-(methylthio)pyridin-3-amine
• CAS NO: 29958-08-5
• Molecular Formula: C₆H₈N₂S
• Molecular Weight: 140.21
• Product Categories: pharmacetical
• Mol File: 29958-08-5.mol
• Article Data: 6

Chemical Properties

• Melting Point: 71-72 °C
• Boiling Point: 332.2°Cat760mmHg
• Flash Point: 154.7°C
• Appearance: /
• Density: 1.2g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.617
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 4.55±0.10(Predicted)
• CAS DataBase Reference: 2-(Methylthio)-5-aminopyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(Methylthio)-5-aminopyridine(29958-08-5)
• EPA Substance Registry System: 2-(Methylthio)-5-aminopyridine(29958-08-5)

Safety Data

• Hazardous Substances Data: 29958-08-5(Hazardous Substances Data)

Usage

General Description

2-(Methylthio)-5-aminopyridine is a chemical compound with the molecular formula C6H7N3S. It is an important intermediate in the synthesis of pharmaceuticals and agrochemicals. 2-(Methylthio)-5-aminopyridine is a derivative of pyridine, which is a heterocyclic organic compound. It is used as a building block in the production of various drugs and as a reagent in organic synthesis. Additionally, it has potential medical uses and is being investigated for its potential to treat neurological disorders. Overall, 2-(Methylthio)-5-aminopyridine is a versatile compound with diverse industrial and pharmaceutical applications.

InChI:InChI=1/C6H8N2S/c1-9-6-3-2-5(7)4-8-6/h2-4H,7H2,1H3

Upstream product

• 4548-45-2 2-chloro-5-nitropyridine 
• 20885-21-6 3-nitro-6-(methylthio)pyridine 
• 13534-97-9 6-bromopyridine-3-amine 
• 5188-07-8 sodium thiomethoxide 

Downstream Products

• 183988-47-8 N-(6-Methylsulfanyl-pyridin-3-yl)-2-(2-oxo-2-phenyl-ethylsulfanyl)-acetamide 
• 1293979-17-5 C₁₃H₁₀F₂N₂OS 
• 34392-80-8 sulfanilic acid-(6-methylsulfanyl-[3]pyridylamide) 

Relevant articles and documents

Discovery of 6,7-dihydro-5H-pyrrolo[2,3-a]pyrimidines as orally available g protein-coupled receptor 119 agonists

GPR119 is a 7-transmembrane receptor that is expressed in the enteroendocrine cells in the intestine and in the islets of Langerhans in the pancreas. Indolines and 6,7-dihydro-5H-pyrrolo[2,3-a]pyrimidines were discovered as G protein-coupled receptor 119

Synthesis of 4- and 6-azaindoles via the fischer reaction

Contrary to the common idea that Fischer indole cyclization often cannot be effectively applied to the synthesis of the corresponding azaindoles, we show that this approach can be actually very efficient for the formation of 4- and 6-azaindoles bearing an electron-donating group on the starting pyridylhydrazines. Two 4-azaindole natural product analogues were synthesized in a few steps and very good overall yields.

p-(sulfonyl) aryl and heteroarylamines as anti-inflammatory agents

This invention relates to anti-inflammatory and analgesic compounds, especially to certain p-(sulfonyl)phenyl amino derivatives, pharmaceutical compositions containing them, methods for their use, and methods for preparing these compounds.