2996-58-9

Basic information

• Product Name: 2-Pyrrolidinone,4-methyl-
• Synonyms: 2-Pyrrolidinone,4-methyl-;4-methyl-2-Pyrrolidinone;4-methyl-2-pyrrolidinone(SALTDATA: FREE)
• CAS NO: 2996-58-9
• Molecular Formula: C₅H₉NO
• Molecular Weight: 99.13
• Product Categories: Aluminium foil bag/Fluoride bottle or on your request
• Mol File: 2996-58-9.mol
• Article Data: 2

Chemical Properties

• Melting Point: 48-51 °C
• Boiling Point: 241℃
• Flash Point: 128℃
• Appearance: /
• Density: 0.979
• Vapor Pressure: 0.0377mmHg at 25°C
• Refractive Index: 1.439
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 16.66±0.40(Predicted)
• CAS DataBase Reference: 2-Pyrrolidinone,4-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyrrolidinone,4-methyl-(2996-58-9)
• EPA Substance Registry System: 2-Pyrrolidinone,4-methyl-(2996-58-9)

Safety Data

• Hazardous Substances Data: 2996-58-9(Hazardous Substances Data)

Usage

Uses

4-Methyl-2-pyrrolidone was used in the preparation of iminopyrrolidines as selective inhibitors of human inducible nitric oxide synthase.

InChI:InChI=1/C5H9NO/c1-4-2-5(7)6-3-4/h4H,2-3H2,1H3,(H,6,7)

Upstream product

• 97-65-4 2-methylenesuccinic acid 

Relevant articles and documents

Graphical method for the determination of the complex NMR shift and equilibrium constant for a hetero-association accompanying self-associations

We describe a novel graphical method which, in conjunction with the previously proposed graphical determination of monomer shift, dimer shift, and dimerization constant for self-association, allows us to determine the complex shift and equilibrium constant for a hetero-association, A + B ? AB, accompanying self-associations, A + A ? A2, and B + B ? B2. The merit of the new method includes the removal of the restrictions imposed on the conventional Benesi-Hildebrand (B-H) plot: (1) that the concentration of one component must be much less than that of the other; (2) that there be no accompanying self-association. The simultaneous equilibrium of the self-association of 2-pyrrolidone (A) and that of 4-methyl-α-pyrrolidone (B) and the hetero-association between A and B in acetonitrile-d3 at 25°C is studied. The inappropriateness of the B-H plot in dealing with this case is also pointed out.