299898-19-4Relevant academic research and scientific papers
Highly enantioselective imine cinnamylation with a remarkable diastereochemical switch
Huber, John D.,Leighton, James L.
, p. 14552 - 14553 (2008/09/19)
The first general method for the enantioselective cinnamylation of aldimines is reported. The method utilizes a simple chiral cinnamylsilane reagent and is characterized by experimental simplicity and extraordinarily high levels of enantioselectivity. Fur
Phenol-directed enantioselective allylation of aldimines and ketimines
Rabbat, Philippe M. A.,Valdez, S. Corey,Leighton, James L.
, p. 6119 - 6120 (2007/10/03)
(Chemical Equation Presented) Phenols are effective directing and activating groups for our allylchlorosilane reagents, allowing the highly enantioselective allylation of a range of 2-aminophenol-derived aldimines. When the phenol is incorporated into the
The first allylation of imines with allyltrichlorosilanes using neutral coordinate-organocatalysts
Sugiura, Masaharu,Robvieux, Fabrice,Kobayashi, Shu
, p. 1749 - 1751 (2007/10/03)
Imines derived from aldehydes and 2-aminophenols reacted with allyltrichlorosilanes in the presence of DMF, HMPA, or pyridine N-oxide as a neutral coordinate-organocatalyst to afford the corresponding homoallylic amines in high yields with high stereosele
Catalytic enantioselective addition of propionate units to imines: An efficient synthesis of anti-α-methyl-β-amino acid derivatives
Kobayashi, Shu,Kobayashi, Jun,Ishiani, Haruro,Ueno, Masaharu
, p. 4185 - 4190 (2007/10/03)
Optically active anti-α-methyl-β-amino acid derivatives have been prepared based on catalytic enantioselective addition of propionate units to simple and inert imines using a chiral zirconium complex. High reactivity and selectivity with wide substrate sc
