299920-47-1

Basic information

• Product Name: 1-Isopropyl-5-oxo-pyrrolidine-3-carboxylic acid
• Synonyms: 3-Pyrrolidinecarboxylicacid,1-(1-methylethyl)-5-oxo-(9CI);Albb-008679;1-isopropyl-5-oxopyrrolidine-3-carboxylic acid(SALTDATA: FREE);1-Isopropyl-2-oxopyrrolidine-4-carboxylic Acid
• CAS NO: 299920-47-1
• Molecular Formula: C₈H₁₃NO₃
• Molecular Weight: 171.2
• Product Categories: ISOPROPYL
• Mol File: 299920-47-1.mol

Chemical Properties

• Boiling Point: 358.3 °C at 760 mmHg
• Flash Point: 170.5 °C
• Appearance: /
• Density: 1.217 g/cm³
• Vapor Pressure: 4.21E-06mmHg at 25°C
• Refractive Index: 1.51
• Storage Temp.: 2-8°C
• PKA: 4.54±0.20(Predicted)
• CAS DataBase Reference: 1-Isopropyl-5-oxo-pyrrolidine-3-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Isopropyl-5-oxo-pyrrolidine-3-carboxylic acid(299920-47-1)
• EPA Substance Registry System: 1-Isopropyl-5-oxo-pyrrolidine-3-carboxylic acid(299920-47-1)

Safety Data

• Hazardous Substances Data: 299920-47-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
1-Isopropyl-5-oxo-pyrrolidine-3-carboxylic acid is used as a building block for the synthesis of collagen, which is essential for the maintenance of connective tissue and skin health. Its role in collagen production makes it a valuable component in the development of treatments for conditions affecting the skin and connective tissues.
Used in Neurotransmitter Synthesis:
Proline is used as a precursor in the biosynthesis of several neurotransmitters, making it an important component in the regulation of the nervous system. Its involvement in neurotransmitter production highlights its potential use in the development of treatments for neurological disorders and mental health conditions.
Used in Dietary Supplements:
As a non-essential amino acid, 1-Isopropyl-5-oxo-pyrrolidine-3-carboxylic acid can be obtained through dietary sources such as meat, dairy, and eggs. However, it is also available as a dietary supplement for individuals who may not be consuming adequate amounts through their diet or for those seeking to support their overall health and well-being.
Used in Research and Development:
Proline's role in protein structure and function makes it a valuable compound for research in the fields of biochemistry, molecular biology, and pharmaceutical development. Its unique properties and functions provide opportunities for the discovery of new therapeutic applications and the advancement of our understanding of protein function in the body.

InChI:InChI=1/C8H13NO3/c1-5(2)9-4-6(8(11)12)3-7(9)10/h5-6H,3-4H2,1-2H3,(H,11,12)

Relevant articles and documents

AZETIDIN-3-YLMETHANOL DERIVATIVES AS CCR6 RECEPTOR MODULATORS

The present invention relates to compounds of Formula (I), their synthesis and use as CCR6 receptor modulators for the treatment or prevention of various diseases, conditions or disorders.

CYCLIC AMINE BASE-1 INHIBITORS HAVING A HETEROCYCLIC SUBSTITUENT

Disclosed are novel compounds of the formula (I)or a pharmaceutically acceptable salt or solvate thereof, wherein R1 is formula (I) X is -0-, -C(R14)2- or -N(R)-; Z is -C(R14)2- or -N(R)-; t is 0, 1, 2 or 3; each R and R2 is independently H, alkyl, cycloalkyl, cycloalkylalkyl, aryl, heteroaryl, heterocycloalkyl, arylalkyl, heteroarylalkyl, heterocycloalkylalkyl, alkenyl or alkynyl; each R14 is H, alkyl, alkenyl, alkynyl, halo, -CN, haloalkyl, cycloalkyl, cycloalkylalkyl, aryl, heteroaryl, heterocycloalkyl, arylalkyl, heteroarylalkyl, heterocycloalkylalkyl, -OR35, -N(R24)(R25)or -SR35; R41 is alkyl, cycloalkyl, -S02(alkyl), -C(O)-alkyl, -C(O)-cycloalkyl or -alkyl-NH-C(O)CH3; and the remaining variables are as defined in the specification. Also disclosed are pharmaceutical compositions comprising the compounds of formula I and methods of treating cognitive or neurodegenerative diseases with compounds of formula (I). Also disclosed are pharmaceutical compositions and methods of treatment comprising compounds of formula I in combination with other agents useful in treating cognitive or neurodegenerative diseases.