299932-83-5Relevant academic research and scientific papers
Synthesis, biological evaluation and molecular modeling of 1,3,4-thiadiazol-2-amide derivatives as novel antitubulin agents
Li, Yu-Jing,Qin, Ya-Juan,Makawana, Jigar A.,Wang, Yan-Ting,Zhang, Yan-Qing,Zhang, Ya-Liang,Yang, Meng-Ru,Jiang, Ai-Qin,Zhu, Hai-Liang
, p. 4312 - 4322 (2014/08/18)
A series of 1,3,4-thiadiazol-2-amide derivatives (6a-w) were designed and synthesized as potential inhibitors of tubulin polymerization and as anticancer agents. The in vitro anticancer activities of these compounds were evaluated against three cancer cel
