299955-06-9

Basic information

• Product Name: 4-chloro-N-[3-(2-naphthylamino)-2-quinoxalinyl]benzenesulfonamide
• Synonyms: 4-chloro-N-[3-(2-naphthylamino)-2-quinoxalinyl]benzenesulfonamide
• CAS NO: 299955-06-9
• Molecular Formula: C24H17ClN4O2S
• Molecular Weight: 460.93538
• Mol File: 299955-06-9.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-chloro-N-[3-(2-naphthylamino)-2-quinoxalinyl]benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chloro-N-[3-(2-naphthylamino)-2-quinoxalinyl]benzenesulfonamide(299955-06-9)
• EPA Substance Registry System: 4-chloro-N-[3-(2-naphthylamino)-2-quinoxalinyl]benzenesulfonamide(299955-06-9)

Safety Data

• Hazardous Substances Data: 299955-06-9(Hazardous Substances Data)

Relevant articles and documents

TARGETING AN HIV-1 NEF-HOST CELL KINASE COMPLEX

Drug candidates for inhibition of HIV-I replication can target Src family kinases (SFK), such as Hck, that interact with Nef protein of the virus. Compounds characterized by such inhibitory activity were identified via an assay for kinase activity of an SFK in a Nef:SFK complex. Illustrative of inhibitors identified using the kinase assay are various 2,3- diaminoquinaxolines and furo[2,3-d]pyrimidines. The inventive inhibitors were found to arrest HIV-I viral replication in vitro.