299965-41-6Relevant academic research and scientific papers
Computational techniques are valuable tools for the discovery of protein-protein interaction inhibitors: The 14-3-3σ case
Corradi, Valentina,Mancini, Manuela,Santucci, Maria Alessandra,Carlomagno, Teresa,Sanfelice, Domenico,Mori, Mattia,Vignaroli, Giulia,Falchi, Federico,Manetti, Fabrizio,Radi, Marco,Botta, Maurizio
supporting information; experimental part, p. 6867 - 6871 (2011/12/22)
Targeting the binding site of 14-3-3 proteins lets the release of partner proteins involved in cell cycle progression, apoptosis, cytoskeletal rearrangement and transcriptional regulation and may therefore be regarded as an alternative strategy to integra
