299966-25-9

Basic information

• Product Name: 8-methoxy-5-nitro-4-(2'-fluorophenyl)quinoline
• Synonyms: 8-methoxy-5-nitro-4-(2'-fluorophenyl)quinoline
• CAS NO: 299966-25-9
• Molecular Weight: 298.273
• Mol File: 299966-25-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 8-methoxy-5-nitro-4-(2'-fluorophenyl)quinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 8-methoxy-5-nitro-4-(2'-fluorophenyl)quinoline(299966-25-9)
• EPA Substance Registry System: 8-methoxy-5-nitro-4-(2'-fluorophenyl)quinoline(299966-25-9)

Safety Data

• Hazardous Substances Data: 299966-25-9(Hazardous Substances Data)

Upstream product

• 1993-03-9 o-fluorophenylboronic acid 
• 145013-65-6 4-Chloro-8-methoxy-5-nitroquinoline 
• 99-59-2 3-amino-4-methoxynitrobenzene 
• 299966-22-6 5-[(2'-methoxy-5'-nitrophenylamino)methylene]-2,2-dimethyl-4,6-dioxo-1,3-dioxane 
• 299966-23-7 8-methoxy-5-nitroquinoline-4-one 

Downstream Products

• 299966-28-2 ethyl 2-[N-[8-methoxy-4-(2'-fluorophenyl)quinolin-5-yl]hydrazono]propionate 
• 299966-26-0 8-methoxy-5-amino-4-(2'-fluorophenyl)quinoline 

Relevant articles and documents

Divergent Syntheses of Pyridoacridine Alkaloids via Palladium-Catalyzed Reductive Cyclization with Nitro-Biarenes

A divergent and novel protocol for the preparation of both pyrido[2,3,4-kl]acridine and pyrido[4,3,2-kl]acridine alkaloids was developed. This method featured the remote palladium-catalyzed reductive cyclization with Mo(CO)6 as reductant. A wide range of substrates including three types of nitro arenes were tolerated and afforded corresponding products in good to excellent yields. This method has been successfully applied to the total synthesis of norsegoline, styelsamine C and the skeleton of necatorone.