299966-85-1

Basic information

• Product Name: (+/-)-2,4-bis(benzyloxy)-6-(4-hydroxy-1-octynyl)-pyrimidine
• Synonyms: (+/-)-2,4-bis(benzyloxy)-6-(4-hydroxy-1-octynyl)-pyrimidine
• CAS NO: 299966-85-1
• Molecular Weight: 416.52
• Mol File: 299966-85-1.mol

Chemical Properties

• CAS DataBase Reference: (+/-)-2,4-bis(benzyloxy)-6-(4-hydroxy-1-octynyl)-pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-2,4-bis(benzyloxy)-6-(4-hydroxy-1-octynyl)-pyrimidine(299966-85-1)
• EPA Substance Registry System: (+/-)-2,4-bis(benzyloxy)-6-(4-hydroxy-1-octynyl)-pyrimidine(299966-85-1)

Safety Data

• Hazardous Substances Data: 299966-85-1(Hazardous Substances Data)

Upstream product

• 1436-34-6 1,2-Epoxyhexane 
• 52517-92-7 1-octyn-4-ol 
• 70523-27-2 2,4-bis(benzyloxy)-6-bromopyrimidine 

Downstream Products

• 299966-83-9 (+/-)-(1Z)-1-[2,6-bis(benzyloxy)-4-pyrimidinyl]-1-octen-4-(ol carbamate) 
• 299966-87-3 (+/-)-1-[2,6-bis(benzyloxy)-4-pyrimidinyl]-1-octyn-4-(ol carbamate) 

Relevant articles and documents

Vinyl and alkynyl pyrimidines as Michael acceptors: An approach to a cylindrospermopsin substructure

Vinyl pyrimidine 9 and alkynyl pyrimidine 24 undergo base-mediated intramolecular conjugate addition reactions in which a carbamate and a urea, respectively, behave as nitrogen nucleophiles. The cyclic carbamate derived from 9 was converted to 11 via a metalation-oxidation reaction in which 2-phenylsulfonyl-3-phenyloxaziridine behaves as a hydroxylation reagent. The cyclic urea derived from 24 was converted to cylindrospermopsin substructure 30 using dimethyldioxirane to introduce the C7 hydroxyl group.