299966-92-0

Basic information

• Product Name: (+/-)-2,4-bis(benzyloxy)-6-[4-(tert-butyldimethylsilyloxy)-1-pentynyl]-pyrimidine
• Synonyms: (+/-)-2,4-bis(benzyloxy)-6-[4-(tert-butyldimethylsilyloxy)-1-pentynyl]-pyrimidine
• CAS NO: 299966-92-0
• Molecular Weight: 488.702
• Mol File: 299966-92-0.mol

Chemical Properties

• CAS DataBase Reference: (+/-)-2,4-bis(benzyloxy)-6-[4-(tert-butyldimethylsilyloxy)-1-pentynyl]-pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-2,4-bis(benzyloxy)-6-[4-(tert-butyldimethylsilyloxy)-1-pentynyl]-pyrimidine(299966-92-0)
• EPA Substance Registry System: (+/-)-2,4-bis(benzyloxy)-6-[4-(tert-butyldimethylsilyloxy)-1-pentynyl]-pyrimidine(299966-92-0)

Safety Data

• Hazardous Substances Data: 299966-92-0(Hazardous Substances Data)

Upstream product

• 80186-44-3 4-<(dimethyl-tert-butylsilyl)oxy>-1-pentyne 
• 70523-27-2 2,4-bis(benzyloxy)-6-bromopyrimidine 

Downstream Products

• 299966-53-3 (+/-)-2,4-bis(benzyloxy)-6-[4-(N-phthalimideoxy)-(1E)-pentenyl]-pyrimidine 
• 299966-49-7 (+/-)-(4E)-5-[2,6-bis(benzyloxy)-4-pyrimidinyl]-4-penten-2-(ol carbamate) 
• 299966-47-5 (+/-)-(4Z)-5-[2,6-bis(benzyloxy)-4-pyrimidinyl]-4-penten-2-(ol carbamate) 
• 299966-96-4 (+/-)-2,4-bis(benzyloxy)-6-[4-(tert-butyldimethylsilyloxy)-(1E)-pentenyl]-pyrimidine 
• 299966-99-7 (+/-)-2,4-bis(benzyloxy)-6-[4-hydroxy-(1E)-pentenyl]-pyrimidine 
• 299966-98-6 (+/-)-2,4-bis(benzyloxy)-6-[4-hydroxy-(1Z)-pentenyl]-pyrimidine 

Relevant articles and documents

Vinyl and alkynyl pyrimidines as Michael acceptors: An approach to a cylindrospermopsin substructure

Vinyl pyrimidine 9 and alkynyl pyrimidine 24 undergo base-mediated intramolecular conjugate addition reactions in which a carbamate and a urea, respectively, behave as nitrogen nucleophiles. The cyclic carbamate derived from 9 was converted to 11 via a metalation-oxidation reaction in which 2-phenylsulfonyl-3-phenyloxaziridine behaves as a hydroxylation reagent. The cyclic urea derived from 24 was converted to cylindrospermopsin substructure 30 using dimethyldioxirane to introduce the C7 hydroxyl group.