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Isoline is an alkaloid derived from Senecio othonniformis, which forms colorless crystals when recrystallized from Me2CO-light petroleum. It has a specific rotation of [α]29D 4.8° (c 1.78, EtOH). Upon alkaline hydrolysis, Isoline yields retronecine, acetic acid, and isolinecic acid. Mass spectral data and chemical degradation studies have identified isolinecic acid as 2,5-dihydroxy-3-methylheptane-2,5-dicarboxylic acid or the 2A-dihydroxy isomer.

30000-36-3

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30000-36-3 Usage

Uses

1. Used in Pharmaceutical Industry:
Isoline is used as a starting material for the synthesis of various pharmaceutical compounds due to its unique chemical structure and properties.
2. Used in Chemical Research:
Isoline serves as a subject of study in chemical research, particularly in the fields of alkaloid chemistry and natural product chemistry, to understand its properties, reactivity, and potential applications.
3. Used in Analytical Chemistry:
Isoline can be used as a reference compound in analytical chemistry for the development and validation of analytical methods, such as mass spectrometry and chemical degradation techniques, due to its distinct chemical features.
4. Used in Toxicology Studies:
Isoline may be utilized in toxicology studies to investigate the effects of alkaloids on biological systems and to understand their potential toxic effects, which can contribute to the development of safer drugs and compounds.
5. Used in Drug Development:
Isoline could be explored for its potential as a therapeutic agent or as a lead compound in drug development, particularly in the context of its alkaline hydrolysis products, such as retronecine and isolinecic acid, which may have pharmacological activities.

References

Gordon-Gray, Coucourakis.,J. Chern. Soc., C, 2312 (1970)

Check Digit Verification of cas no

The CAS Registry Mumber 30000-36-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,0,0,0 and 0 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 30000-36:
(7*3)+(6*0)+(5*0)+(4*0)+(3*0)+(2*3)+(1*6)=33
33 % 10 = 3
So 30000-36-3 is a valid CAS Registry Number.
InChI:InChI=1/C20H29NO7/c1-5-20(25)10-12(2)19(4,28-13(3)22)17(23)26-11-14-6-8-21-9-7-15(16(14)21)27-18(20)24/h6,12,15-16,25H,5,7-11H2,1-4H3/t12-,15-,16-,19+,20-/m1/s1

30000-36-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name (12S,15R)-15-Hydroxy-11,16-dioxo-15,20-dihydrosenecionan-12-yl ac etate

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:30000-36-3 SDS

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