30000-87-4

Usage

Chemical Class

Indole derivatives
A class of heterocyclic aromatic organic compounds

Molecular Weight

341.41 g/mol
The mass of one mole of the compound, measured in grams

Derivative of Indole

A modified version of the parent compound indole, which is a heterocyclic aromatic organic compound

Contains two phenyl groups

Two groups consisting of a six-membered carbon ring with alternating single and double bonds

Methoxy group on the 7th position of the indole ring

A methoxy group (-OCH3) attached to the nitrogen-containing ring at the 7th position

Potential Applications

Pharmaceutical field

Anticancer properties

Capable of inhibiting or preventing the growth of cancer cells

Antimicrobial properties

Effective in combating and destroying microorganisms like bacteria and fungi

Antiviral properties

Capable of inactivating or preventing the replication of viruses

Further Research

Necessary to explore specific properties and potential uses
Additional studies and investigations may be required to fully understand the compound's characteristics and possible applications in various fields

Upstream product

• 91-23-6 2-Nitroanisole 
• 501-65-5 diphenyl acetylene 
• 90-04-0 2-methoxy-phenylamine 
• 34159-01-8 deoxybenzoin o-methoxyphenylhydrazone 

Downstream Products

• 83824-14-0 7-Methoxy-2,3-diphenyl-indole-1-carbaldehyde 

Relevant academic research and scientific papers

Step and redox efficient nitroarene to indole synthesis

Step and redox efficiencies are a rising priority in synthetic method development, in order to make synthetic processes more sustainable and more affordable. Herein, a step and redox efficient nitroarene to indole synthesis is developed, in sharp contrast to the rich literature on the construction of indoles. Elemental zinc was found to be the best terminal reductant. This journal is

A Fast Track to Indoles and Annulated Indoles through ortho- vs ipso-Amination of Aryl Halides

A complementary site selective ortho- vs ipso-amination of aryl halides using non-electrophilic amine sources for construction of indole scaffolds is reported. A palladium-catalyzed alkyne insertion/C-H activation/palladacycle amination via merger of three easily diversified components including iodoarenes, alkynes, and amines delivers indoles with different substitution patterns even in gram scales. By employing ortho-bromoanilines, a consecutive annulative π-extension of indoles proceeds to construct indolo[1,2-f]phenanthridine scaffolds via four C-C and C-N bond formations in one pot.

SUBSTITUENT INFLUENCE ON THE INDOLIZATION WITH PCl3 OF SOME o,m,p-SUBSTITUTED PHENYLHYDRAZONES

The indolization of deoxybenzoin o,m,p (Me, MeO, Cl), p-NO2 and m-EtO-phenylhydrazones (1) by the above reaction has been examined.All the reactions are carried out at room temperature and high yields of the corresponding indoles (2) are obtained even whe