30007-57-9

Basic information

• Product Name: 2-bromo-3-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propanoic acid
• CAS NO: 30007-57-9
• Molecular Formula: C₁₁H₈BrNO₄
• Molecular Weight: 298.0895
• Mol File: 30007-57-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 445.4°C at 760 mmHg
• Flash Point: 223.2°C
• Density: 1.808g/cm³
• Vapor Pressure: 1.02E-08mmHg at 25°C
• Refractive Index: 1.66
• CAS DataBase Reference: 2-bromo-3-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromo-3-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propanoic acid(30007-57-9)
• EPA Substance Registry System: 2-bromo-3-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propanoic acid(30007-57-9)

Safety Data

• Hazardous Substances Data: 30007-57-9(Hazardous Substances Data)

Upstream product

• 85-44-9 phthalic anhydride 

Downstream Products

• 39739-03-2 4-(1,3-dioxo-1,3-dihydroisoindol-2-yl)-butyric acid methyl ester 
• 54238-27-6 methyl (E)-4-(1,3-dioxoisoindolin-2-yl)but-2-enoate 

Relevant articles and documents

Convergent Route to β-Amino Acids and to β-Heteroarylethylamines: An Unexpected Vinylation Reaction

Various protected β2-amino acids can be prepared by radical addition of β-phthalimido-α-xanthyl propionic acid, both as the free acid or as the ethyl ester. Successive radical additions provide access to more complex structures. In the case of the free acid, addition to certain heteroaromatics leads directly to β-heteroarylethylamines through spontaneous decarboxylation of the intermediate adduct. Forcing the decarboxylation in some cases generated a vinyl group by decarboxylative elimination of the phthalimido group.