30010-06-1Relevant articles and documents
7-Amino-2-aryl/hetero-aryl-5-oxo-5,8-dihydro[1,2,4]triazolo[1,5-a]pyridine-6-carbonitriles: Synthesis and adenosine receptor binding studies
Shaik, Khasim,Deb, Pran Kishore,Mailavaram, Raghu Prasad,Chandrasekaran, Balakumar,Kachler, Sonja,Klotz, Karl-Norbert,Jaber, Abdul Muttaleb Yousef
, p. 1568 - 1573 (2019/05/27)
A series of novel 7-amino-5-oxo-2-substituted-aryl/hetero-aryl-5,8-dihydro[1,2,4]triazolo[1,5-a]pyridine-6-carbonitriles (4a–4t) was synthesized, characterized and evaluated for their binding affinity and selectivity towards hA1, hA2A/sub
Microwave assisted synthesis and evaluation of N-cinnamoyl aryl hydrazones for cytotoxic and antioxidant activities
Devi, T. Sarala,Rajitha
, p. 1703 - 1709 (2016/08/06)
A series of N-cinnamoyl aryl hydrazones 2a-2i were synthesized in good yields by microwave irradiation technique. The title compounds were formed by nucleophilic condensation of various N1- substituted benzylidene-2-cyano aceto hydrazides with
The Complex Reaction of Acetohydrazides with Unsaturated Diketones: Alternative Cyclizations to 1,2-Diazepin-3-ones and Pyrazolopyridines
Alonso, Paloma,Martin-Leon, Nazario,Quinteiro, Margarita,Seoane, Carlos,Soto, Jose L.
, p. 841 - 846 (2007/10/02)
The reaction of 2-cyanoacetohydrazide (1) and 2-(ethoxycarbonyl)acetohydrazide (26) with unsaturated 1,3-diketones leading with moderate yields to 1,2-diazepinones (3, 23, 24) and pyrazolopyridines (5, 15, 20, 25) together with the corresponding acetohydrazones have been studied.The reaction course depends on the temperature and the relative reactivity of the carbonyl groups of the starting materials.When one of these carbonyl groups is less reactive (benzoyl or ethoxycarbonyl groups), the reaction does not yield diazepinones but only pyrazolopyridines and/or acetohydrazones.
