30034-22-1

Upstream product

• 1529770-73-7 N-(2-nitrobenzyloxycarbonyl)-L-alanine methyl ester 
• 1529770-75-9 N-(2-nitrobenzyloxycarbonyl)-L-alanine (acridin-9-yl)methyl ester 
• 1529770-77-1 N-(2-nitrobenzyloxycarbonyl)-L-alanine [11-oxo-2,3,5,6,7,11-hexahydro-1H-pyrano[2,3-f]pyrido[3,2,1-ij]quinolin-9-yl]methyl ester 
• 612-25-9 2-Nitrobenzyl alcohol 

Downstream Products

• 56-41-7 L-alanin 
• 29809-25-4 2-nitrosobenzaldehyde 
• 1529770-75-9 N-(2-nitrobenzyloxycarbonyl)-L-alanine (acridin-9-yl)methyl ester 
• 1529770-77-1 N-(2-nitrobenzyloxycarbonyl)-L-alanine [11-oxo-2,3,5,6,7,11-hexahydro-1H-pyrano[2,3-f]pyrido[3,2,1-ij]quinolin-9-yl]methyl ester 

Relevant academic research and scientific papers

Wavelength-selective cleavage of o-nitrobenzyl and polyheteroaromatic benzyl protecting groups

Evaluation of the wavelength-selective cleavage of five photolabile protecting groups from two different families has been performed. Alanine, as a model bifunctional target molecule was masked at the amino terminal with o-nitrobenzyl group and at the carboxylic terminal with benzyl-type nitrogen and oxygen polyheteroaromatics, namely acridine, (thioxo)benzocoumarin and a coumarin built on the julolidine nucleus. The photosensitivity of the corresponding alanine conjugates was studied at selected wavelengths with HPLC/UV and 1H NMR monitoring. The release of the fully deprotected molecule could be achieved by sequential irradiation in variable irradiation times, which were dependent on the heteroaromatic group used.