30039-44-2Relevant academic research and scientific papers
New alkyne esters and alkyneamide plant antibacterial agents
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Paragraph 0083-0086; 0102, (2022/03/02)
The present invention relates to a class of propyne esters and propyneamide compounds and synthetic methods thereof, and drugs containing the compound and applications thereof. The two types of compounds have efficient and broad-spectrum inhibitory activity for more than ten kinds of plant pathogenic fungi, and at the same time have the characteristics of simple structure, easy large-scale preparation and high safety of animals and plants, and can be used as active ingredients for the development of new plant antibacterial agents with high efficiency and low toxicity.
Facile construction of thermo-responsive Pickering emulsion for esterification reaction in phase transfer catalysis system
Lei, Manjun,Shen, Yifeng,Sun, Jie,Yang, Lei,Yang, Lihui,Zhao, Qiangqiang,Zhao, Xiao
, (2020/12/30)
In this paper, a thermo-responsive Pickering emulsion (PE) is constructed for the esterification reaction in the phase transfer catalysis (PTC) system. Silica nanoparticle modified by alkyl polyoxyethylene ether and tetrabutylammonium bromide (TBAB) is the highly efficient thermo-responsive Pickering emulsifier to stabilize the diisopropyl ketone-in-water emulsion. PEs can keep stable at room temperature for 3 days and demulsify only in the condition of elevated temperature and agitation, which causes the easy product separation and aqueous phase recycling. The adsorption of TBA+ and nonionic surfactant via electrostatic interaction and hydrogen bonding, respectively, can increase the hydrophobicity and the emulsifying capacity of silica nanoparticle. The ion-pair of TBA+ and reactant anion is generated and can be transferred into the organic phase, initiating the bond-forming reaction. The modifying effect of polyoxyethylene ether is weakened with the increase of temperature due to the loss of the hydrogen bonding interaction, resulting in the demulsification of PEs. Moreover, the cloud point of polyoxyethylene ether is the temperature for the complete separation of two phases. In this PTC system, the conversion rate for the esterification can reach to 92 % and the aqueous phase can be reused at least 5 times without sacrifice of the catalytic activity, demonstrating the potential application in industry.
Oxidative activation of dihydropyridine amides to reactive acyl donors
Funder, Erik Daa,Trads, Julie B.,Gothelf, Kurt V.
supporting information, p. 185 - 198 (2015/01/16)
Amides of 1,4-dihydropyridine (DHP) are activated by oxidation for acyl transfer to amines, alcohols and thiols. In the reduced form the DHP amide is stable towards reaction with amines at room temperature. However, upon oxidation with DDQ the acyl donor is activated via a proposed pyridinium intermediate. The activated intermediate reacts with various nucleophiles to give amides, esters, and thio-esters in moderate to high yields. This journal is
Sodium Borohydride-Carboxylic Acid Systems - A new Method of Acylation of Alcohols, Phenols and Thiophenols
Prashad, Mahavir,Jigajinni, Veerappa B.
, p. 822 - 823 (2007/10/02)
A new method of acylation of alcohols, phenols and thiophenols in sodium borohydride-carboxylic acid system is described.A plausible mechanism of this acylation through tetraacyloxyborate derivative has been postulated.
