30044-85-0 Usage
Uses
Used in Pharmaceutical Applications:
Chelirubine Chloride is used as a therapeutic agent for various medical conditions, including immunological or metabolic dysfunction, cancer, bacterial, fungal, and viral infections, radiation damage, epilepsy, multiple sclerosis, skin diseases, postoperative wounds, pain, sleeping disorders, herpes infections, influenza virus infections, skin tumors, allergies, chronic fatigue syndrome, osteoporosis, rheumatic diseases, and scars.
Used in Anticancer Applications:
Chelirubine Chloride is used as an anticancer agent, targeting a wide range of malignancies. It has been subjected to numerous pharmacological tests, including its quaternary ammonium reaction product with thiotepa, which has demonstrated potential in the treatment of cancer.
Used in Drug Delivery Systems:
To enhance the efficacy and bioavailability of Chelirubine Chloride, various drug delivery systems have been developed. These systems aim to improve the compound's delivery to target tissues, ensuring optimal therapeutic outcomes while minimizing potential side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 30044-85-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,0,0,4 and 4 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 30044-85:
(7*3)+(6*0)+(5*0)+(4*4)+(3*4)+(2*8)+(1*5)=70
70 % 10 = 0
So 30044-85-0 is a valid CAS Registry Number.
30044-85-0Relevant academic research and scientific papers
Conversion of the Naturally Occurring Amide Alkaloids into O5 Benzophenanthridinium Alkaloids. A New Synthetic Sequence to Antitumour Benzophenanthridine Alkaloids
Ishii, Hisashi,Ishikawa, Tsutomu,Watanabe, Toshiko,Ichikawa, Yuh-Ichiro,Kawanabe, Eri
, p. 2283 - 2290 (2007/10/02)
Cyclisation of methyl integriamide (17a) and methyl isoarnottianamide (17b) by the Bischler-Napieralski reaction gave the naturally occurring O5 benzophenanthridine alkaloids, chelirubine (5a), and chelilutine (5b), respectively; this was extended to give a generally applicable, versatile synthesis of benzophenanthridine alkaloids from 2-aryl-3,4-dihydronaphthalen-1(2H)-ones (13).Treatment of the tetralones (13) with methylamine and titanium tetrachloride followed by sodium borohydride provided the cis-2-aryl-N-methyl-1,2,3,4-tetrahydro-1-naphthylamines (14) which were converted into the N-formyl derivatives (15) with freshly prepared chloral in good yields.Dehydrogenation of the resulting formamides (15) with 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) gave the fully aromatised amines corresponding to methyl integriamide (17a).Bischler-Napieralski reaction of these amides (17) furnished the desired quaternary benzophenanthridine alkaloids (5).
