3005-52-5Relevant academic research and scientific papers
Nitrous Oxide as a Hydrogen Acceptor for the Dehydrogenative Coupling of Alcohols
Gianetti, Thomas L.,Annen, Samuel P.,Santiso-Quinones, Gustavo,Reiher, Markus,Driess, Matthias,Grützmacher, Hansj?rg
supporting information, p. 1854 - 1858 (2016/02/03)
The oxidation of alcohols with N2O as the hydrogen acceptor was achieved with low catalyst loadings of a rhodium complex that features a cooperative bis(olefin)amido ligand under mild conditions. Two different methods enable the formation of either the corresponding carboxylic acid or the ester. N2 and water are the only by-products. Mechanistic studies supported by DFT calculations suggest that the oxygen atom of N2O is transferred to the metal center by insertion into the Rh-H bond of a rhodium amino hydride species, generating a rhodium hydroxy complex as a key intermediate.
