300555-66-2

Basic information

• Product Name: ((4S,5S)-4,5-Diphenyl-[1,3]dioxolan-2-yl)-acetic acid tert-butyl ester
• Synonyms: ((4S,5S)-4,5-Diphenyl-[1,3]dioxolan-2-yl)-acetic acid tert-butyl ester
• CAS NO: 300555-66-2
• Molecular Weight: 340.419
• Mol File: 300555-66-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ((4S,5S)-4,5-Diphenyl-[1,3]dioxolan-2-yl)-acetic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: ((4S,5S)-4,5-Diphenyl-[1,3]dioxolan-2-yl)-acetic acid tert-butyl ester(300555-66-2)
• EPA Substance Registry System: ((4S,5S)-4,5-Diphenyl-[1,3]dioxolan-2-yl)-acetic acid tert-butyl ester(300555-66-2)

Safety Data

• Hazardous Substances Data: 300555-66-2(Hazardous Substances Data)

Upstream product

• 13831-03-3 tert-butyl prop-2-ynoate 
• 2325-10-2 (S,S)-hydrobenzoin 

Downstream Products

• 2325-10-2 (S,S)-hydrobenzoin 

Relevant articles and documents

New protecting groups for 1,2-diols (boc- and moc-ethylidene). Cleavage of acetals with bases

1,2-Diols react at rt with alkyl propynoates, in the presence of 4-dimethylaminopyridine, to give cyclic acetals which are quite stable to acid-catalyzed hydrolysis or methanolysis. 1,3-Diols and 1,4-diols do not form acetals with alkyl propynoates under the same conditions. Deprotection is accomplished with bases (via elimination and addition/elimination steps).