30057-76-2

Basic information

• Product Name: N-(2-oxoheptan-3-yl)acetaMide
• Synonyms: N-(2-oxoheptan-3-yl)acetaMide;N-(1-Acetyl-pentyl)-acetamide
• CAS NO: 30057-76-2
• Molecular Formula: C₉H₁₇NO₂
• Molecular Weight: 171
• Mol File: 30057-76-2.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(2-oxoheptan-3-yl)acetaMide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-oxoheptan-3-yl)acetaMide(30057-76-2)
• EPA Substance Registry System: N-(2-oxoheptan-3-yl)acetaMide(30057-76-2)

Safety Data

• Hazardous Substances Data: 30057-76-2(Hazardous Substances Data)

Usage

General Description

N-(2-Oxoheptan-3-yl)acetamide is a chemical compound with the molecular formula C9H17NO2. It is an acetamide derivative with a heptan-3-yl group attached to the nitrogen atom. This chemical is often used as an intermediate in organic synthesis and pharmaceutical research. N-(2-Oxoheptan-3-yl)acetamide has potential applications in the development of new drugs and can also be used as a precursor for the synthesis of various other organic compounds. Its unique chemical structure and properties make it a valuable building block for the creation of new compounds with diverse applications in different industries.

Upstream product

• 616-06-8 2-amino-hexanoic acid 
• 108-24-7 acetic anhydride 
• 109-69-3 n-Butyl chloride 
• 7737-16-8 N-acetamidoacetone 

Downstream Products

• 40513-33-5 3-aminoheptan-2-one 
• 5467-73-2 3-amino-heptan-2-one; hydrochloride 

Relevant articles and documents

New N6- or N(9)-hydroxyalkyl substituted 8-azaadenines or adenines as effective A1 adenosine receptor ligands.

In this paper we describe synthesis and biological assays of some A(1) ligands more water-soluble than the effective, but very lipophilic, 8-azaadenines and adenines discovered in the past and obtained introducing on N(6) or N(9) substituent a hydroxy group. Five of the new N(6)-hydroxyalkyl- and N(6)-hydroxycycloalkyl-2-phenyl-9-benzyl-8-azaadenines showed very high affinity (Ki40 nM) and selectivity for A(1) adenosine receptors. Among the 2-phenyl-9-(2-hydroxy-3-alkyl)-8-azaadenines or adenines prepared, the compounds with the higher A(1) affinity and selectivity resulted 2-phenyl-9-(2-hydroxy-3-propyl)-N(6)-cyclopentyl- and cyclohexyl-8-azaadenine with Ki 2.2+/-0.2 nM and 2.8+/-0.3 nM respectively. From the point of view of water-solubility, 2-phenyl-9-(2-hydroxy-3-propyl)-8-azaadenine was the most interesting compound, having a CLogP of 1.066991 and a water-solubility of 1.2 mg mL(-1).