300588-82-3Relevant academic research and scientific papers
EIS INHIBITORS
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Paragraph 0019; 0125, (2018/06/30)
Compounds and compositions are disclosed, which are useful as inhibitors of acetyltransferase Eis, a mediator of kanamycin resistance in Mycobacterium tuberculosis.
Discovery and Optimization of Two Eis Inhibitor Families as Kanamycin Adjuvants against Drug-Resistant M. tuberculosis
Garzan, Atefeh,Willby, Melisa J.,Green, Keith D.,Tsodikov, Oleg V.,Posey, James E.,Garneau-Tsodikova, Sylvie
supporting information, p. 1219 - 1221 (2016/12/18)
Drug-resistant tuberculosis (TB) is a global threat and innovative approaches such as using adjuvants of anti-TB therapeutics are required to combat it. High-throughput screening yielded two lead scaffolds of inhibitors of Mycobacterium tuberculosis (Mtb)
