30067-11-9

Basic information

• Product Name: (2,4-DICHLOROPHENYL)ACETALDEHYDE
• Synonyms: (2,4-DICHLOROPHENYL)ACETALDEHYDE;Benzeneacetaldehyde, 2,4-dichloro-
• CAS NO: 30067-11-9
• Molecular Formula: C₈H₆Cl₂O
• Molecular Weight: 189.04
• Product Categories: Aromatic Aldehydes & Derivatives (substituted)
• Mol File: 30067-11-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 269.4±25.0 °C(Predicted)
• Appearance: /
• Density: 1.317±0.06 g/cm3(Predicted)
• CAS DataBase Reference: (2,4-DICHLOROPHENYL)ACETALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: (2,4-DICHLOROPHENYL)ACETALDEHYDE(30067-11-9)
• EPA Substance Registry System: (2,4-DICHLOROPHENYL)ACETALDEHYDE(30067-11-9)

Safety Data

• Hazardous Substances Data: 30067-11-9(Hazardous Substances Data)

Usage

General Description

(2,4-Dichlorophenyl)acetaldehyde, also known as 2,4-DCPA, is an organic compound with the chemical formula C8H6Cl2O. It is a colorless liquid with a bitter, almond-like odor, and it is considered a potential environmental contaminant. This chemical is commonly used as a building block in the synthesis of pharmaceuticals and agrochemicals. It is also used as a pesticide, particularly in the control of broadleaf weeds in various crops. 2,4-DCPA can be toxic if ingested or inhaled in large amounts, and the Environmental Protection Agency has set regulations for its safe use and handling. Additionally, it has been linked to negative impacts on aquatic organisms and may pose a risk to human health and the environment if not properly managed.

Upstream product

• 94-99-5 2,4-Dichlorobenzyl chloride 
• 68-12-2 N,N-dimethyl-formamide 
• 55954-23-9 methyl 2-(2,4-dichlorophenyl)acetate 
• 81156-68-5 2,4-dichlorophenylethyl alcohol 

Downstream Products

• 1580465-96-8 N¹-(2,4-dichlorophenethyl)-N³,N³-dimethylpropane-1,3-diamine 
• 172321-34-5 2-(2,4-dichlorobenzyl)-4,5-diphenylimidazole 
• 1345673-42-8 2-acetamido-N-tert-butyl-2-(3-(2,4-dichlorophenethylamino)propyl)-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)hexanamide 
• 1188446-70-9 ethyl 4-(2,4-dichlorophenyl)isoxazole-3-carboxylate 
• 292601-09-3 2,4-dichlorophenylacetaldehyde N,N-dimethylhydrazone 
• 431948-25-3 (E)-4-[2-(2,4-dichlorophenyl)ethenyl]morpholine 

Relevant articles and documents

HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE

The present invention relates to compounds and methods which may be useful as inhibitors of GPR119 for the treatment or prevention of metabolic, cardiovascular, and metabolic diseases.

Design and biological evaluation of phenyl-substituted analogs of β-phenylethylidenehydrazine

β-Phenylethylidenehydrazine (PEH) has been demonstrated previously to be an inhibitor of γ-aminobutyric acid transaminase (GABA-T) and to cause a marked increase in rat brain levels of GABA, a major neurotransmitter. A group of PEH analogs, possessing a variety of substituents (Me, OMe, Cl, F, and CF3) at the 2-, 3-, and 4-positions of the phenyl ring, were synthesized for evaluation as inhibitors of GABA-T. The details of the synthesis and chemical characterization of the analogs are described. Preliminary in vitro screening for GABA-T inhibition showed that all the analogs possessed activity against this enzyme, although substitution of CF3 at the 2- and 4-positions caused reduced activity. One of the drugs, 4-fluoro-β- phenylethylidenehydrazine, was investigated further ex vivo, where it was shown to inhibit GABA-T, elevate brain levels of GABA, and decrease levels of glutamine, similar to the profile observed previously for PEH.