300699-53-0

Basic information

• Product Name: (E)4-Iodostyryl₄-Fluorobenzylsulfone
• Synonyms: (E)4-Iodostyryl₄-Fluorobenzylsulfone
• CAS NO: 300699-53-0
• Molecular Weight: 402.228
• Mol File: 300699-53-0.mol

Chemical Properties

• CAS DataBase Reference: (E)4-Iodostyryl₄-Fluorobenzylsulfone(CAS DataBase Reference)
• NIST Chemistry Reference: (E)4-Iodostyryl₄-Fluorobenzylsulfone(300699-53-0)
• EPA Substance Registry System: (E)4-Iodostyryl₄-Fluorobenzylsulfone(300699-53-0)

Safety Data

• Hazardous Substances Data: 300699-53-0(Hazardous Substances Data)

Upstream product

• 222639-41-0 2-[(4-fluorobenzyl)sulfonyl]acetic acid 
• 15164-44-0 p-(iodophenyl)carboxaldehyde 

Relevant articles and documents

(E)-styryl sulfone anticancer agents

(E)-styryl benzylsulfones of formula I are useful as anticancer agents: wherein R1, R2, R3, and R4 are independently selected from the group consisting of hydrogen, fluoro, chloro, iodo, bromo, C1-C6 alkyl, C1-C4 alkoxy, nitro, cyano and trifluoromethyl, with the proviso that (a) R1, R2 , and R3 not all hydrogen when R4 is 2-chloro or 4-chloro; (b) when R1 and R3 are hydrogen and R2 is 4-bromo or 4-chloro, then R4 may not be 4-chloro, 4-fluoro or 4-bromo; (c) when R1 and R3 are hydrogen and R2 is 4-fluoro, then R4 may not be 4-fluoro or 4-bromo, (d) when R1 is hydrogen, and R4 is 2-fluoro, the R2 and R3 may not be 4-fluoro; and (e) when R1 is hydrogen and R3 is 4-hydrogen, 4-chloro, 4-bromo, 4-methyl or 4-methoxy, and R4 is 2-hydrogen, 2-chloro, or 2-fluoro; then R2 may not be 4-hydrogen, 4-chloro, 4-fluoro, or 4-bromo.