30078-67-2

Usage

General Description

1-Propanone, 1-(3-furanyl)-, also known as furfuralacetone, is a chemical compound that is derived from furfural, which is found in agricultural byproducts such as corncobs and sugarcane bagasse. It is a colorless liquid with a strong, sweet smell, and it is used as a flavoring agent in various food products. Furfuralacetone is also used in the production of resins, plastics, and pharmaceuticals, and it has potential applications in the synthesis of fine chemicals and pharmaceutical intermediates. However, it is important to handle furfuralacetone with caution as it is flammable and can cause skin and eye irritation.

Upstream product

• 26214-65-3 furan-3-carbonyl chloride 
• 925-90-6 ethylmagnesium bromide 
• 66346-65-4 1-(furan-3-yl)propan-1-ol 
• 498-60-2 furan-3-carboxaldehyde 
• 852998-61-9 1-(furan-3-yl)prop-2-en-1-ol 

Downstream Products

• 106475-46-1 1-[3]furyl-propan-1-one-(4-phenyl semicarbazone) 
• 108539-94-2 1-[3]furyl-propan-1-one-(4-nitro-phenylhydrazone) 

Relevant academic research and scientific papers

Tethered η5-oxocyclohexadienyl piano-stool ruthenium(II) complexes: A new class of catalysts?

The straightforward synthesis of tethered η5-oxocyclohexadienyl Ru(II) complexes is presented. Pioneering results in catalysis show that these original half-sandwich Ru(II) complexes allow the effective isomerization of allylic alcohols under mild conditions without further additives; η5-oxocyclohexadienyl ruthenium complexes may be considered as a new class of catalysts.

Cp*Ru(PN) complex-catalyzed isomerization of allylic alcohols and its application to the asymmetric synthesis of muscone

Highly efficient isomerization of allylic alcohols into saturated carbonyls is accomplished using the catalyst system of Cp*RuCl[Ph2P(CH2)2NH2-κ2-P,N]-KOt-Bu (Cp* = η5-C5(CH3)5) under mild conditions. Mechanistic consideration based on isotope-labeling experiments indicated the present reaction is applicable to the asymmetric isomerization of racemic sec-allylic alcohols with a prochiral olefin via dynamic kinetic resolution. A concise asymmetric synthesis of muscone has been achieved, where the asymmetric isomerization using an optically active ligand is a key reaction. Copyright

Substituted heterocyclylisoquinolinium salts and compositions and method of use thereof

Substitutued heterocyclylisoquinolinium salts, pharmaceutical compositions containing them and methods for the treatment or prevention of neurodegenerative disorders or neurotoxic injuries utilizing them.

Substituted 6,11-ethano-6,11-dihydrobenzo[b] quinolizinium salts and compositions and methods of use thereof

Substituted 6,11-ethano-6,11-dihydrobenzo[b]quinolizinium salts, pharmaceutical compositions containing them, and methods for the treatment of neurodegenerative disorders or neurotoxic injuries utilizing them, wherein the substituted 6,11-ethano-6,11-dihydrobenzo[b]quinolizinium salts have the formula: STR1 wherein: R1, R2, R3, R4, R5, R6, R7, X and p are as defined in the specification.

Stereoselective Reduction of γ-Oxobutanoic Acids Using DIBAL-H and ZnCl2

A variety of γ-aromatic γ-ketobutanoic acids can be reduced selectively, under optimized conditions, by the use of DIBAL-H and ZnCl2 to provide the (RS,SR)-γ-aryl-γ-hydroxy-β-methylbutanoic acids.Further evidence has been gathered to support the hypothesis that the reaction proceeds by formation of a seven-membered ring complex with the aluminium or zinc atom bridging the ketone and carboxyl groups which preceeds the reduction step and that this templated reduction accounts for observed high diastereoselectivity.Also we have shown that some γ-aryl-γ-butyrolactones can be easily transformed via an oxidative cleavage of the aromatic ring to provide selective synthesis of either cis- or trans-tetrahydro-3-methyl-5-oxo-2-furancarboxylic acid derivatives.