301157-63-1Relevant academic research and scientific papers
Two approaches to the transformation of (benzimidazol-2-ylmethyl)triphenylphosphonium chloride into the derivatives of pyrimido[1,6-a]benzimidazole
Smolii,Muzychka,Chernega,Drach
, p. 1703 - 1708 (2007/10/03)
The reaction of readily accessible (benzimidazol-2-ylmethyl)triphenylphosphonium chloride with acyl isothiocyanates in the presence of triethylamine, as well as consecutive treatment of the above phosphonium salt first with N,N-dimethylformamide dimethyl acetal and then with phenyl or allyl isothiocyanate gives two types of phosphorus-containing derivatives of pyrimido[1,6-a]benzimidazole with the thione group in position 3 or 1 of the condensed system. The structure of one of compounds of the first type, 3-thioxo-1-p-tolyl-3,4-dihydropyrimido[1,6-a] benzimidazol-4-ylidenetriphenylphosphorane, was determined by single crystal X-ray diffraction.
