301162-83-4

Upstream product

• 14199-15-6 Methyl 4-hydroxyphenylacetate 
• 288399-19-9 4-(chloromethyl)-2-methylquinoline 
• 301162-82-3 [4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-acetic acid methyl ester 

Downstream Products

• 1429654-24-9 C₁₉H₁₆FNO₂ 
• 362703-02-4 C₂₄H₂₄N₂O₄ 

Relevant academic research and scientific papers

Beta-amino acid derivatives as inhibitors of matrix metalloproteases and TNF-alpha

The present application describes novel β-amino acid derivatives of formula I: or pharmaceutically acceptable salt or prodrug forms thereof, wherein A, X, Z, Ua, Xa, Ya, Za, R1, R2, R3

Hydantoins and related heterocycles as inhibitors of matrix metalloproteinases and/or TNF-alpha converting enzyme (TACE)

The present application describes novel hydantoin derivatives of formula (I): or pharmaceutically acceptable salt or prodrug forms thereof, wherein A, B, R1, R2, R3, R4, R5, R6, R7, R11, and n are defined in the present specification, which are useful as inhibitors of matrix metalloproteinases (MMP), TNF-α converting enzyme (TACE), aggrecanase, or a combination thereof.