30117-44-3

Usage

Uses

Used in Industrial Production:
(2R)-2-hydroxyoctanoic acid is used as a raw material for the production of plasticizers and lubricants, enhancing the performance and functionality of these materials.
Used in Pharmaceutical Synthesis:
(2R)-2-hydroxyoctanoic acid is used as a key intermediate in the synthesis of various pharmaceuticals, contributing to the development of new drugs and treatments.
Used in Food Industry:
(2R)-2-hydroxyoctanoic acid is used as a natural preservative for its antimicrobial properties, helping to inhibit the growth of certain bacteria and fungi, thus improving food safety and shelf life.
Used in Cosmetic Industry:
(2R)-2-hydroxyoctanoic acid is used as an ingredient in cosmetics for its antimicrobial properties, ensuring the safety and efficacy of cosmetic products.

InChI:InChI=1/C8H16O3/c1-2-3-4-5-6-7(9)8(10)11/h7,9H,2-6H2,1H3,(H,10,11)/t7-/m1/s1

Upstream product

• 617-73-2 2-hydroxy-octanoic acid 
• 124-07-2 Octanoic acid 

Relevant academic research and scientific papers

Biocatalytic Oxidative Cascade for the Conversion of Fatty Acids into α-Ketoacids via Internal H2O2 Recycling

The functionalization of bio-based chemicals is essential to allow valorization of natural carbon sources. An atom-efficient biocatalytic oxidative cascade was developed for the conversion of saturated fatty acids to α-ketoacids. Employment of P450 monooxygenase in the peroxygenase mode for regioselective α-hydroxylation of fatty acids combined with enantioselective oxidation by α-hydroxyacid oxidase(s) resulted in internal recycling of the oxidant H2O2, thus minimizing degradation of ketoacid product and maximizing biocatalyst lifetime. The O2-dependent cascade relies on catalytic amounts of H2O2 and releases water as sole by-product. Octanoic acid was converted under mild conditions in aqueous buffer to 2-oxooctanoic acid in a simultaneous one-pot two-step cascade in up to >99 % conversion without accumulation of hydroxyacid intermediate. Scale-up allowed isolation of final product in 91 % yield and the cascade was applied to fatty acids of various chain lengths (C6:0 to C10:0).