3013-97-6

Usage

Uses

Used in Pharmaceutical Industry:
Cytidylyl-(5'->3')-uridine is used as a therapeutic agent for the treatment of various diseases, including cancer and viral infections. Its role in RNA synthesis and gene expression makes it a potential target for the development of drugs that modulate these processes.
Used in Biotechnology Industry:
Cytidylyl-(5'->3')-uridine is used as a building block for the synthesis of RNA molecules in various biotechnological applications, such as RNA interference, gene therapy, and the development of RNA-based vaccines.
Used in Research and Development:
Cytidylyl-(5'->3')-uridine is used as a research tool for studying the structure, function, and regulation of RNA molecules. It is also used in the development of new techniques and methods for RNA analysis and manipulation.
Used in Diagnostics:
Cytidylyl-(5'->3')-uridine can be used as a biomarker for the detection and monitoring of various diseases, including genetic disorders and infections. Its involvement in gene expression and protein synthesis makes it a valuable indicator of cellular processes and dysfunctions.

Upstream product

• 1379659-43-4 cytidine 5’-monophosphate imidazolide 
• 58-96-8 uridine 
• 63-37-6 cytidine monophosphate 

Downstream Products

• 606-02-0 uridine 2',3'-cyclic phosphate 
• 65-46-3 CYTIDINE 

Relevant academic research and scientific papers

A nucleotide dimer synthesis without protecting groups using montmorillonite as catalyst

A synthesis has been developed providing nucleotide dimers comprising natural or unnatural nucleoside residues. A ribonucleoside 5-phosphorimidazolide is added to a nucleoside adsorbed on montmorillonite at neutral pH with the absence of protecting groups. Approximately 30% of the imidazolide is converted into each 2-5 dimer and 3-5 dimer with the rest hydrolyzed to the 5-monophosphate. Experiments with many combinations have suggested the limits to which this method may be applied, including heterochiral and chimeric syntheses. This greener chemistry has enabled the synthesis of dimers from activated nucleotides themselves, activated nucleotides with nucleosides, and activated nucleotides with nucleotide 5-monophosphates.

SITE-SPECIFIC MODIFICATION OF THE PYRIMIDINE RESIDUE DURING THE DEPROTECTION OF THE FULLY-PROTECTED DIURIDYLIC ACID.

A study of four different O-4 and N-3 protected uridine derivatives, 4 to 7, for their stabilities under different conditions versus their abilities to undergo nucleophilic substitution reaction at C-4 by an appropriate oxygen or a nitrogen nucleophile has established a general strategy for the site-specific modification of a particular pyrimidine residue in a model fully protected diuridylic acid to give either UpC, CpC or UpU, depending upon the deprotection condition.