301320-10-5Relevant academic research and scientific papers
Copper-doped mesoporous silica supported dual acidic ionic liquid as an efficient and cooperative reusability catalyst for Biginelli reaction
Yao, Nan,Lu, Ming,Liu, Xiao Bing,Tan, Jin,Hu, Yu Lin
, p. 328 - 335 (2018)
A series of MCM-41 supported functionalized ionic liquids doped with copper species were prepared, characterized and evaluated as catalysts in the Biginelli reaction. Most of these supported ionic liquids perform well in the reaction, especially the multifunctional copper coordinated MCM-41 supported heterogeneous catalysts (0.5)IL-TiCl5@MCM-41@Cu(15) and (0.5)IL-HSO4@MCM-41@Cu(15). The catalytic tests revealed that (0.5)IL-HSO4@MCM-41@Cu(15) was the best and powerful catalyst in the Biginelli reaction for the preparation of 3,4-dihydropyrimidinones with high to excellent yields. The catalyst can be easily separated from the reaction mixture by filtration and reused in six consecutive cycles without significant loss in catalytic activity.
Synthesis, Crystal Structure, and Spectroscopic Properties of 5-Ethoxycarbonyl-4-[(4-methoxy-carbonyl)phenyl] -6-methyl-3,4-dihydropyrimidin2(1H)-ones
Peng,Zheng,Zeng,Hu,Ye
, p. 266 - 276 (2015)
The title compound, 5-ethoxycarbonyl-4-[(4-methoxycarbonyl)phenyl]-6-methyl-3,4-dihydropyrimidin-2(1H)-ones (1), was synthesized from the one-pot, three-component condensation reactions and characterized by FTIR, 1H NMR, HRMS, and single crysta
Synthesis and antimicrobial activity of 3,4-dihydropyrimidin-2(1H)-one derivatives containing a hydrazone moiety
Peng, Hua-Nan,Ye, Li-Min,Zhang, Ming,Yang, Yan-Chun,Zheng, Jie
, p. 113 - 117 (2018)
The title compounds were synthesized and characterized by IR, 1H NMR, 13C NMR and HRMS data. Their antimicrobial activities against bacterial strains Escherichia coli and fungal strains Aspergillus Niger were evaluated.
A microwave-assisted, copper-catalyzed three-component synthesis of dihydropyrimidinones under mild conditions
Pasunooti, Kalyan Kumar,Chai, Hua,Jensen, Chantel Nixon,Gorityala, Bala Kishan,Wang, Siming,Liu, Xue-Wei
supporting information; experimental part, p. 80 - 84 (2011/02/25)
The synthesis of dihydropyrimidinones via a clean multi-component Biginelli reaction under microwave irradiation is reported. The copper-catalyzed process proved to be simple, efficient, economical, and environmentally friendly.
Bronsted acidic ionic liquid-catalyzed one-pot synthesis of 3,4-dihydropyrimidin-2(1h)-ones and thiones under solvent-free conditions
Hajipour, Abdol R.,Khazdooz, Leila,Zarei, Amin
experimental part, p. 2200 - 2208 (2011/06/27)
An efficient and convenient procedure for the synthesis of 3,4-dihydropyrimidin- 2(1H)-ones and thiones by condensation of ethylacetoacetate, aldehydes, and urea or thiourea in the presence of methylimidazolium hydrogensulfate is described. Aromatic and a
