301355-05-5

Basic information

• Product Name: 1-({2-nitrophenyl}sulfonyl)indoline
• Synonyms: 1-({2-nitrophenyl}sulfonyl)indoline
• CAS NO: 301355-05-5
• Molecular Formula: C₁₄H₁₂N₂O₄S
• Molecular Weight: 304.32108
• Mol File: 301355-05-5.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-({2-nitrophenyl}sulfonyl)indoline(CAS DataBase Reference)
• NIST Chemistry Reference: 1-({2-nitrophenyl}sulfonyl)indoline(301355-05-5)
• EPA Substance Registry System: 1-({2-nitrophenyl}sulfonyl)indoline(301355-05-5)

Safety Data

• Hazardous Substances Data: 301355-05-5(Hazardous Substances Data)

Upstream product

• 496-15-1 1-indoline 
• 1694-92-4 2-Nitrobenzenesulfonyl chloride 
• 434934-80-2 N-(o-nitrobenzenesulfonyl)-o-iodophenethylamine 
• 434934-79-9 N-(o-nitrobenzenesulfonyl)-o-bromophenethylamine 

Downstream Products

• 954587-88-3 1-(2-aminobenzenesulfonyl)indoline 
• 1233701-23-9 5-chloro-1-[(2-nitrophenyl)sulfonyl]indoline 
• 1233701-26-2 7-[(2-nitrophenyl)sulfonyl]indoline 

Relevant articles and documents

NRF2 SMALL MOLECULE INHIBITORS FOR CANCER THERAPY

Small molecule inhibitors of Nrf2 and methods of their use are provided for treating or preventing a disease, disorder or condition associated with an Nrf2- regulated pathway. The compound can be administered as a single agent or can be administered to enhance the efficacy of a chemotherapeutic drug and/or radiation therapy.

Rearrangement of indolinesulfonamides to sulfones using polyphosphoric acid (PPA)

Unlike other N-alkylsulfonanilides, indolinesulfonamides hydrolyze in 98% sulfuric acid. Recent work in this laboratory has shown that rearrangement can be achieved by using polyphosphoric acid. A series of substituted indolinesulfonamides has been prepar

A mild inter- and intramolecular amination of aryl halides with a combination of CuI and CsOAc

A unique combination of CuI and CsOAc was found to catalyze aryl amination under mild conditions. The reaction takes place at room temperature or at 90 °C with broad functional group compatibility. The intramolecular reaction was able to form five-, six-, and seven-membered rings with various protecting groups on the nitrogen atom. The scope of the intermolecular amination, as well as its applications to unsymmetrical N,N′-dialkylated phenylenediamines, was investigated.