301359-46-6Relevant academic research and scientific papers
Metal- And Oxidant-Free Electrochemical Oxidative Desulfurization C-O Coupling of Thiourea-Type Compounds with Alcohols
Cao, Bao-Qian,Quan, Zheng-Jun,Ren, Ming-Zhe,Wang, Xi-Cun,Zhu, Zheng-He
, p. 1634 - 1642 (2020)
An efficient desulfurization C-O coupling reaction of 3,4-dihydropyrimidine-2(1 H)-thiones (including thioureas) with alcohols was developed under electrochemical oxidation conditions. Herein, transition--metal catalysts and additives are not required and
Structure-based designing, solvent less synthesis of 1,2,3,4-tetrahydropyrimidine-5-carboxylate derivatives: A combined in vitro and in silico screening approach
Ahmad, Zaheer,Ahmed, Sibtain,Akhtar, Naseem,Arshad, Uzma,Hassan, Aqsa,Mehmood, Tahir,Parveen, Shagufta,Shafiq, Nusrat
, (2021/08/03)
Objective: In this study, small molecules possessing tetrahydropyrimidine derivatives have been synthesized having halogenated benzyl derivatives and carboxylate linkage. As previously reported, FDA approved halogenated pyrimidine derivatives prompted us
UV-Light-Irradiated Trifluoromethylation of Diheteroaryl Disulfides with CF3SO2Na
Cao, Bao-Qian,Qiu, Yi-Feng,Zhang, Xi,Zhu, Zheng-He,Quan, Zheng-Jun,Wang, Xi-Cun
supporting information, p. 1208 - 1214 (2019/02/07)
A simple protocol for the UV light irradiated preparation of heteroaryl trifluoromethyl thioethers from disulfides and inexpensive, environmentally sodium triflinate (CF3SO2Na) has been developed. The features of simple and clean rea
Synthesis of dihydropyrimidin-2-one/thione library and cytotoxic activity against the human U138-MG and Rat C6 glioma cell lines
Canto, Ro?mulo F.S.,Bernardi, Andressa,Battastini, Ana Maria O.,Russowsky, Dennis,Eifler-Lima, Vera Lucia
experimental part, p. 1379 - 1388 (2012/04/17)
Two series of 4-aryl-3,4-dihydropyrimidin-2(1H)-(thio)ones including monastrol (1a), have been synthesized by an environment-friendly methodology based on the combined use of citric acid or oxalic acid and TEOF (triethylorthoformate). The library was eval
Synthesis and inhibitory activity against Epstein-Barr virus of some new 1,2,3,4-tetrahydropyrimidine-2-thiones
Attaby, Fawzy A.,Ramla, Mostafa M.,Harukuni
experimental part, p. 2956 - 2967 (2009/09/06)
1,2,3,4-Tetrahydropyrimidine-2-thiones 4a-n were synthesized through the reaction of aromatic aldehydes 1a-n, ethyl acetoacetate (2) and thiourea (3). The structures of all newly synthesized heterocyclic compounds elucidated by the use of IR, 1H NMR, mass
