301532-91-2Relevant academic research and scientific papers
Stereocontrolled access to orthogonally protected anti,anti-4- aminopiperidine-3,5-diols through chemoselective reduction of enantiopure β-lactam cyanohydrins
Alcaide, Benito,Almendros, Pedro,Cabrero, Gema,Ruiz, M. Pilar
, p. 7980 - 7991 (2008/02/13)
(Chemical Equation Presented) The cyanosilylation of enantiopure 4-oxoazetidine-2-carbaldehydes with tert-butyldimethylsilyl cyanide was promoted by either molecular sieves or catalytic amount of sodium carbonate to give O-silylated β-lactam cyanohydrins
Diastereoselectivity enhancement in the 1,3-cycloaddition of β-lactam aldehydes. Application to the synthesis of enantiopure indolizidinone amino esters
Alcaide, Benito,Almendros, Pedro,Redondo, Maria C.,Ruiz, M. Pilar
, p. 8890 - 8894 (2007/10/03)
Enantiopure α-alkoxy β-lactam acetaldehydes were prepared via the thiazole-based one-carbon homologation. The 1,3-dipolar cycloaddition reaction involving α-alkoxy β-lactam acetaldehyde-derived azomethine ylides gave with excellent diastereoselectivity hi
Polyhydroxy amino acid derivatives via β-lactams using enantiospecific approaches and microwave techniques
Bose, Ajay K.,Banik, Bimal K.,Mathur, Chandra,Wagle, Dilip R.,Manhas, Maghar S.
, p. 5603 - 5619 (2007/10/03)
Enantiospecific synthesis has been developed for α-hydroxy β-lactams of predictable absolute configuration starting with readily available carbohydrates. Stereospecific approaches and microwave assisted chemical reactions have been utilized for the prepar
