301541-32-2

Basic information

• Product Name: 2-chloro-N-(2-oxoethyl)-N-(phenylmethyl)acetamide
• Synonyms: 2-chloro-N-(2-oxoethyl)-N-(phenylmethyl)acetamide
• CAS NO: 301541-32-2
• Molecular Weight: 225.675
• Mol File: 301541-32-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-chloro-N-(2-oxoethyl)-N-(phenylmethyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-N-(2-oxoethyl)-N-(phenylmethyl)acetamide(301541-32-2)
• EPA Substance Registry System: 2-chloro-N-(2-oxoethyl)-N-(phenylmethyl)acetamide(301541-32-2)

Safety Data

• Hazardous Substances Data: 301541-32-2(Hazardous Substances Data)

Upstream product

• 100129-49-5 N-benzyl-2-chloro-N-(2-hydroxyethyl)acetamide 

Downstream Products

• 32705-80-9 1,4-dibenzylpiperazin-2-one 

Relevant articles and documents

Efficient synthesis of substituted piperazinones via tandem reductive amination-cyclization

A new strategy for the preparation of substituted piperazinones features a tandem reductive coupling and S(N)2-cyclization of a 2-chloro-N-(2-oxoalkyl)acetamide (1) and a primary amine (2). The method is convenient for diversity-oriented synthesis, since a wide variety of amines may be used in the ring-forming reaction to produce N-substituted piperazinones (3). (C) 2000 Published by Elsevier science Ltd.