30160-92-0Relevant academic research and scientific papers
Sodium halides as the source of electrophilic halogens in green synthesis of 3-halo- and 3,n-dihalobenzo[b]thiophenes
Kesharwani, Tanay,Kornman, Cory,Tonnaer, Amanda,Hayes, Amanda,Kim, Seoyoung,Dahal, Nikesh,Romero, Ralf,Royappa, Andrew
, p. 2973 - 2984 (2018/05/23)
A convenient methodology for the synthesis of mono- and di-halogenated benzo[b]thiophenes is described herein, which utilizes copper(II) sulfate pentahydrate and various sodium halides in the presence of substituted 2-alkynylthioanisoles. The proposed met
Synthesis of 2,3-disubstituted benzo[b]thiophenes via palladium-catalyzed coupling anphilic cyclization of terminal acetylenes
Yue, Dawei,Larock, Richard C.
, p. 1905 - 1909 (2007/10/03)
2,3-Disubstituted benzo[b]thiophenes have been prepared in excellent yields via coupling of terminal acetylenes with commercially available o-iodothioanisole in the presence of a palladium catalyst and subsequent electrophilic cyclization of the resulting
Synthesis of benzo[b]thiophenes by electrophilic cyclization
Larock, Richard C,Yue, Dawei
, p. 6011 - 6013 (2007/10/03)
2,3-Disubstituted benzo[b]thiophenes are readily prepared in excellent yields under very mild reaction conditions by the Pd/Cu-catalyzed cross-coupling of commercially available o-iodothioanisole and terminal alkynes, followed by electrophilic cyclization
