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2H-Benz[g]indazole-2-acetamide,3-[(4-chlorophenyl)amino]-4,5-dihydro-N-(1-methylethyl)- is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

301644-22-4

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301644-22-4 Usage

Chemical compound

2H-Benz[g]indazole-2-acetamide,3-[(4-chlorophenyl)amino]-4,5-dihydro-N-(1-methylethyl)-

Class

Indazole derivatives

Function

Potent and selective inhibitor of phosphodiesterase 10A

Target

Enzyme regulating cAMP levels

Potential uses

Treatment of neurological and psychiatric disorders such as schizophrenia and Parkinson's disease

Mechanism of action

Modulates activity of neurotransmitter systems in the brain

Promising candidate for

Development of novel pharmacological treatments for neurological and psychiatric conditions

Check Digit Verification of cas no

The CAS Registry Mumber 301644-22-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,0,1,6,4 and 4 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 301644-22:
(8*3)+(7*0)+(6*1)+(5*6)+(4*4)+(3*4)+(2*2)+(1*2)=94
94 % 10 = 4
So 301644-22-4 is a valid CAS Registry Number.

301644-22-4Downstream Products

301644-22-4Relevant academic research and scientific papers

N-Substituted 3-(arylamino)-4,5-dihydro-2H-benz[g]indazol-2-yl acetamides with anti-inflammatory and analgesic activities

Schenone, Silvia,Bruno, Olga,Ranise, Angelo,Bondavalli, Francesco,Falcone, Giuseppe,Filippelli, Walter,Rivaldi, Barbara

, p. 383 - 388 (2007/10/03)

A series of substituted 3-(arylamino)-4,5-dihydro-2H-benz[g]indazol-2-yl acetamides was synthesized and tested in comparison with former analogues. The title compounds showed only weak antiarrhythmic properties but good anti- inflammatory and antinociceptive activity, particularly evident in the morpholino derivative. (C) 2000 Published by Elsevier Science S.A.

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