301672-68-4

Upstream product

• 76008-73-6 5-Bromo-2-chloro-benzoic acid ethyl ester 
• 112275-50-0 tert-butyl 1,4-diazepine-1-carboxylate 
• 3375-31-3 palladium diacetate 

Downstream Products

• 301673-05-2 4-[4-Chloro-3-[[(2-tricyclo[3.3.1.13,7]dec-1-ylethyl)amino]carbonyl]phenyl]hexahydro-1H-1,4-diazepine-1-carboxylic acid, 1,1-dimethylethyl ester 
• 301672-69-5 4-(3-Carboxy₄-chlorophenyl)hexahydro-1H-1,4-diazepine-1-carboxylic acid, 1,1-dimethylethyl ester 

Relevant academic research and scientific papers

HEDGEHOG PATHWAY ANTAGONISTS AND THERAPEUTIC APPLICATIONS THEREOF

Heterocyclic compounds that modulate the hedgehog signaling pathway, pharmaceutical composition thereof and their therapeutic applications.

Adamantane derivatives

The invention provides compounds of general formula in which m, A, R1and Ar have the meanings defined in the specification; a process for their preparation; pharmaceutical compositions containing them; a process for preparing the pharmaceutical compositions; and their use in therapy.