301681-83-4Relevant academic research and scientific papers
Synthesis and biological activities of some new thiazolidine-4-ones and pyrimidines incorporating benzo (b) thiophene
Tirlapur, Vijay Kumar,Ohawan, Aditya
, p. 141 - 144 (2013/09/23)
Thiazolidine-4-ones and pyrimidines incorporating benzo (o) thiophene have been prepared starting from 3-chlorobenzo(6) thiophen-2-carbonyl chloride. All the newly synthesized compounds were characterized by elemental analysis, IR 1H NMR and ma
Synthesis of heterocycles from the products of anionic arylation of unsaturated compounds. 7*. Products of haloarylation of acrylic acid and its esters in the synthesis of benzo[b]thiophene derivatives
Obushak,Matiichuk,Martyak
, p. 878 - 884 (2007/10/03)
3-Chloro-2-chlorocarbonylbenzo[b]thiophenes were obtained on oxidation of Meerwein reaction products, viz. 3-aryl-2-halopropionic acids and their esters, with thionyl chloride in the presence of N-benzyl-N-methylmorpholinium chloride. Disubstituted thioureas were synthesized by the reaction of these compounds with ammonium thiocyanate and aromatic amines, and were cyclized by interaction with iodoacetic acid with the formation of 4-thiazolidinone derivatives. The same cyclization in the presence of aromatic aldehydes leads to the formation of the corresponding 5-arylidene-substituted 4-thiazolidinones.
