301685-57-4Relevant academic research and scientific papers
Peptide deformylase inhibitors with activity against respiratory tract pathogens
East, Stephen P.,Beckett, R. Paul,Brookings, Daniel C.,Clements, John M.,Doel, Sheila,Keavey, Kenneth,Pain, Gilles,Smith, Helen K.,Thomas, Wayne,Thompson, Alison J.,Todd, Richard S.,Whittaker, Mark
, p. 59 - 62 (2007/10/03)
A series of analogues of the peptide deformylase (PDF) inhibitor BB-3497 where the P3′ amide bond was replaced with a ketone functionality is described. The in vitro antibacterial profiling of these compounds revealed that they demonstrate activity agains
