301808-65-1Relevant academic research and scientific papers
Zn(Proline)2-catalyzed Knoevenagel condensation under solventfree/aqueous conditions and biological evaluation of products
Siddiqui, Zeba N.,Musthafa, T. N. Mohammed,Praveen, Shagufta,Farooq, Farheen
, p. 1438 - 1444 (2011)
A novel approach was adopted for the synthesis of series of Knoevenagel condensation products from 5-chloro-3-methyl-1-phenylpyrazole-4-carboxaldehyde with different cyclic active methylene compounds, using water soluble and recyclable Zn(Proline)2 as a Lewis acid catalyst both under solvent-free condition and using water as a reaction medium in good yields. In each conversion, the catalyst was successfully recovered and recycled without significant loss in yield and selectivity. The compounds were screened for their antimicrobial activity. Springer Science+Business Media, LLC 2010.
P2O5/SiO2 as an efficient heterogeneous catalyst for the synthesis of heterocyclic alkene derivatives under thermal solvent-free conditions
Siddiqui, Zeba N.,Khan, Tabassum
, p. 2032 - 2043 (2013/07/26)
A highly efficient methodology is developed for the synthesis of a series of heterocyclic alkene derivatives 3a-k from 5-chloro-3-methyl-1-phenylpyrazole- 4-carboxaldehyde 1 and active methylene compounds 2a-k, in the presence of P2O5/sub
